NIMONIDIP 60

NIMONIDIP 60 is a prescription calcium channel blocker tablet from Steris Healthcare, made for use in neurological care. Each tablet contains Nimodipine IP 60 mg.

Calcium channel blockers are best known for lowering blood pressure, but nimodipine is different. It is a dihydropyridine that is highly lipophilic (fat-soluble), so it crosses the blood-brain barrier easily and acts preferentially on the small arteries of the brain. This selectivity is why nimodipine is used in neurology rather than as a routine blood pressure medicine.

Product Information 

How Does Nimodipine Work?

Smooth muscle in the walls of blood vessels needs calcium to enter the cells to contract. Nimodipine blocks L-type calcium channels, so less calcium enters and the vessel wall relaxes.

After a ruptured brain aneurysm, blood in the space around the brain irritates the arteries and can trigger cerebral vasospasm, a dangerous narrowing of the vessels. This usually occurs several days after the bleed and can cut off blood supply to parts of the brain, leading to delayed cerebral ischaemia and stroke-like damage.

Nimodipine helps by:

• Relaxing and protecting the cerebral arteries from spasm
• Limiting calcium overload inside brain cells, which is a key step in ischaemic injury
• Supporting blood flow to vulnerable brain tissue

It is important to be clear that nimodipine improves outcomes in SAH. It does not reliably reverse angiographic vasospasm itself, and the exact mechanism of its benefit is still being studied.

Why Is NIMONIDIP 60 Important?

A subarachnoid haemorrhage is a life-threatening emergency. Even among survivors of the initial bleed, delayed cerebral ischaemia in the following days and weeks is a major cause of disability and death. Treating the aneurysm itself, by surgical clipping or endovascular coiling, deals with the bleeding source, but it does not remove the later danger from vasospasm.

This is where oral nimodipine has a firmly established role. Clinical trials and international guidelines support starting nimodipine early after SAH and continuing it for 21 days, because it has been shown to improve functional outcomes. It is one of very few drugs with this level of evidence in the condition.

Why it matters in practice:

• Evidence-backed: it is the standard oral drug used after aneurysmal SAH.
• Targets the brain: its selectivity for cerebral vessels sets it apart from other calcium channel blockers.
• Reduces disability: the goal is to help patients recover with better neurological function.
• Simple to give: an oral tablet that can also be crushed for patients with feeding tubes, as directed by the care team.

For neurosurgeons, neurologists, critical care teams, hospital pharmacists and distributors, a reliable nimodipine tablet is an essential line in the neurology and critical care portfolio.

Key Benefits 

• Improves neurological outcome after SAH: the principal, best-evidenced benefit.
• Reduces the risk of delayed cerebral ischaemia: protects against damage from vasospasm.
• Brain-selective action: acts mainly on cerebral arteries because it is lipophilic.
• Oral convenience: a 60 mg tablet that suits scheduled 4-hourly dosing.
• Established guideline support: widely used as part of standard SAH care.
• Can be used in patients who cannot swallow: tablets can be prepared for nasogastric administration under clinical supervision.
• Reliable strength: a standardised 60 mg dose supports accurate scheduling.
• Quality-assured manufacturing: made by Steris Healthcare in a WHO-GMP and ISO certified facility.
• Practical strip of 10: convenient for dispensing and ward-level stock management.

Uses of NIMONIDIP 60 

On a doctor's advice, nimodipine tablets are used in:

• Aneurysmal subarachnoid haemorrhage (SAH): to improve neurological outcome by reducing the effects of delayed cerebral ischaemia (the main, well-established use)
• Prevention and treatment of cerebral vasospasm after SAH, in line with specialist care
• Other cerebrovascular conditions, in some regions and by specialist judgement (for example, certain cases of vascular cognitive impairment or migraine prophylaxis). These are often off-label or country-specific.

Precautions and Warnings

Do not use NIMONIDIP 60 if you:

• Are allergic to nimodipine or any ingredient in the tablet
• Are taking strong CYP3A4 inhibitors such as certain azole antifungals or HIV protease inhibitors without specialist advice
• Have a condition where the product's label lists a contraindication (verify against the final insert)

Inform your doctor before use if you have:

• Low blood pressure or unstable blood pressure
• Liver disease, particularly cirrhosis
• Heart problems, including a very slow heartbeat or heart failure
• Raised pressure inside the skull or brain swelling (cerebral oedema)
• Kidney disease
• Plans to become pregnant, or if you are pregnant or breastfeeding

Possible Side Effects

Common:

• Low blood pressure (hypotension)
• Headache
• Flushing (warmth and redness of the face)
• Dizziness
• Nausea
• Swelling of the ankles or feet

Less common:

• Slow heartbeat (bradycardia) or fast heartbeat (tachycardia)
• Palpitations
• Stomach upset, diarrhoea or constipation
• Skin rash or itching
• Sweating
• Tiredness or weakness

Frequently Asked Questions 

Where can I buy nimodipine 60 mg online?
Nimodipine 60 mg can be purchased through authorized pharmacies and pharmaceutical sellers, subject to prescription and applicable local requirements.

What is the price of nimodipine 60 mg?
The price of nimodipine 60 mg may vary depending on the brand, dosage form, pack size, seller, and applicable offers. Check the current listed price before ordering.

Can I order nimodipine 60 mg online?
Yes, nimodipine 60 mg may be ordered online from an authorized medicine seller when the product is available and applicable prescription requirements are met.

Is nimodipine 60 mg available from Steris Healthcare?
Availability depends on the current Steris Healthcare product range and stock. Check the relevant Steris Healthcare product listing for current availability.

What is nimodipine 60 mg used for?
Nimodipine is a calcium-channel blocker used in adults following subarachnoid hemorrhage (SAH) caused by a ruptured intracranial aneurysm to reduce the incidence and severity of ischemic neurological deficits.

What is the composition of nimodipine 60 mg?
The active ingredient is nimodipine 60 mg. The inactive ingredients may vary depending on the specific brand and dosage form.

Is a prescription required?
Nimodipine is a prescription medicine and should be used only under the supervision of a qualified healthcare professional.

How should nimodipine 60 mg be taken?
Take nimodipine exactly as prescribed by your doctor. For the FDA-approved oral solution for subarachnoid hemorrhage, the labeled dose is 60 mg every 4 hours for 21 consecutive days, beginning within 96 hours of the onset of SAH. It should be administered enterally and must not be administered intravenously.

What should I know before buying nimodipine 60 mg?
Check the strength, dosage form, manufacturer, expiry date, storage instructions, and product authenticity before purchasing. Nimodipine can lower blood pressure, so medical supervision and blood-pressure monitoring may be required during treatment.

How can I order nimodipine 60 mg online?
Select nimodipine 60 mg from an authorized pharmaceutical seller, verify the product details and prescription requirements, provide the required delivery information, and complete the available payment process.