MAGRAL 80

MAGRAL 80 is a prescription hormonal tablet. Each tablet contains Megestrol Acetate IP 80 mg. Megestrol acetate is a synthetic derivative of progesterone, the natural female sex hormone. Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO 9001-certified pharmaceutical manufacturer based in Jaipur, Rajasthan, makes and markets it.

Hormone-sensitive cancers such as some breast and endometrial cancers depend on the body's own hormones to grow. Megestrol acetate acts on progesterone receptors and changes the hormonal environment those tumour cells rely on. It is also thought to lower the release of pituitary hormones that drive oestrogen production, and it may have a direct effect on tumour cells. Together these actions can slow disease progression and ease symptoms in advanced or recurrent disease.

Megestrol acetate also stimulates appetite. For this reason it is sometimes used by specialists to manage loss of appetite and weight loss in serious illness. Check whether this use is covered by your product label, because it may be an off-label or specialist-directed use for the tablet form.

Product Information 

Why Is Megestrol Acetate Important?

Advanced breast and endometrial cancers are difficult to treat. When surgery or radiotherapy is no longer an option, hormonal therapy is an important way to slow disease and preserve quality of life. Megestrol acetate matters for four reasons.

1. Targeted hormonal approach. It suits cancers whose growth is hormone-driven. It is generally better tolerated than many cytotoxic chemotherapy regimens.
2. Oral convenience. A tablet can be taken at home, so patients need fewer hospital visits.
3. Appetite and weight support. Weight loss and poor appetite are common in advanced cancer and worsen outcomes and energy. Megestrol acetate's appetite-stimulating effect can help here under specialist supervision.
4. Long clinical track record. It has been used for decades, so its safety profile and monitoring needs are well understood.

Uses of MAGRAL 80

• Palliative treatment of advanced (recurrent, inoperable or metastatic) breast cancer
• Palliative treatment of advanced endometrial carcinoma (cancer of the uterine lining)
• Management of appetite loss and weight loss (cachexia) in selected patients, at the specialist's discretion 

Key Benefits 

• Slows hormone-sensitive tumour growth. It works on the hormonal pathways that fuel some breast and endometrial cancers.
• Improves appetite. It can help patients eat better and support nutrition during illness.
• Helps stabilise body weight. This is meaningful in cancer-related weight loss.
• Supports energy and well-being. Better nutrition and disease control can improve day-to-day quality of life.
• Convenient oral dosing. The tablet can be taken at home with or without food.
• Manufactured to quality standards. Steris Healthcare operates a WHO-GMP and ISO 9001 certified facility, with quality checks at each stage.
• Flexible dosing. The 80 mg strength lets physicians build the total daily dose in divided amounts, for example two tablets for 160 mg.

Precautions and Warnings

Do not use MAGRAL 80 if:

• You are pregnant or planning pregnancy. Megestrol acetate can harm an unborn baby.
• You are allergic to megestrol acetate or any tablet ingredient.

Tell your doctor before starting if you have:

• A history of blood clots, deep vein thrombosis, stroke or pulmonary embolism. Megestrol can increase clotting risk.
• Diabetes or high blood sugar. It may raise blood glucose and change your medicine needs.
• High blood pressure, heart disease or fluid retention.
• Liver or kidney problems.
• Undiagnosed vaginal bleeding.

Side Effects

Not everyone gets side effects. Common ones include:

• Increased appetite and weight gain
• Nausea or vomiting
• Swelling of the feet or hands (fluid retention)
• Hot flashes
• Breathlessness
• Headache or tiredness
• Breakthrough vaginal spotting or bleeding
• Mild hair thinning

Frequently Asked Questions

1. Where can I buy megestrol acetate online?
Megestrol acetate may be available through licensed pharmacies and authorized pharmaceutical suppliers. Always purchase from a reliable source and verify the product, manufacturer, and packaging before use.

2. What is the price of megestrol acetate?
The price of megestrol acetate depends on the strength, dosage form, pack size, manufacturer, and seller. Please check the current product listing or contact the supplier for the latest price.

3. Can I order megestrol acetate online?
Yes, megestrol acetate may be ordered online where legally permitted. Because it is a prescription medicine, you may be required to provide a valid prescription before purchase.

4. Is megestrol acetate available from Steris Healthcare?
Availability of megestrol acetate from Steris Healthcare can vary. Please check the current Steris Healthcare product listing or contact the company directly to confirm availability, strength, pack size, and ordering details.

5. What is megestrol acetate used for?
Megestrol acetate is a progestin medicine used for specific medical conditions, including certain cancers and, in some formulations, to help manage significant loss of appetite and weight loss associated with serious illness. Its use depends on the prescribed formulation and the patient's medical condition.

6. What is the composition of megestrol acetate?
The active pharmaceutical ingredient is megestrol acetate. The exact strength and inactive ingredients depend on the specific product and dosage form. Always check the product packaging or prescribing information for complete composition details.

7. Is a prescription required for megestrol acetate?
Megestrol acetate is generally a prescription medicine. It should be used only under the direction of a qualified healthcare professional, who can determine whether it is appropriate for you.

8. How should megestrol acetate be taken?
Take megestrol acetate exactly as prescribed by your doctor. The dose and duration depend on the condition being treated and the specific formulation. Do not change the dose, stop treatment, or take it more frequently without medical advice.

9. What should I know before buying megestrol acetate?
Before purchasing megestrol acetate, confirm the strength, dosage form, pack size, manufacturer, expiry date, and prescription requirements. Tell your doctor about your existing medicines and medical conditions so potential risks and interactions can be considered.

10. How can I order megestrol acetate online?
To order megestrol acetate online, choose a licensed and trustworthy pharmacy or authorized supplier, select the prescribed strength and pack size, provide a valid prescription if required, and complete the ordering process according to the seller's instructions.