LTROLAMINE 50

Low platelet counts, medically known as thrombocytopenia, can lead to serious health complications if not addressed promptly. Patients may experience frequent bruising, prolonged bleeding, or increased susceptibility to infections. In modern medicine, Eltrombopag Olamine, the active component of LITROLAMINE 50 Tablets, has emerged as a reliable solution for managing low platelet levels effectively.

LITROLAMINE 50 contains Eltrombopag Olamine 50 mg, a potent thrombopoietin receptor agonist that stimulates the production of platelets in the body. It is widely prescribed for adults with conditions such as immune thrombocytopenic purpura (ITP), chronic liver disease-related thrombocytopenia, and other disorders where platelet counts are abnormally low.

Understanding Thrombocytopenia and Its Risks

What is Thrombocytopenia?

Thrombocytopenia refers to a decrease in the number of platelets in the blood. Platelets are essential for blood clotting and preventing excessive bleeding. A low platelet count can lead to:

• Easy bruising

• Frequent nosebleeds or gum bleeding

• Prolonged bleeding after minor cuts

• Fatigue or weakness

Left untreated, severe thrombocytopenia may result in life-threatening bleeding events.

Causes of Low Platelet Count

Some common causes of thrombocytopenia include:

• Immune Thrombocytopenic Purpura (ITP) – an autoimmune condition where the body attacks its own platelets

• Chronic liver disease – affecting platelet production

• Bone marrow disorders – reducing platelet synthesis

• Medications – certain drugs can suppress platelet formation

• Viral infections – such as dengue or hepatitis

Composition of LITROLAMINE 50 Tablets

Eltrombopag Olamine 50 mg

Eltrombopag Olamine is a thrombopoietin receptor agonist. It stimulates the bone marrow to produce more platelets, thereby helping patients maintain a safer platelet count.

Key properties:

• Increases platelet production in the bone marrow

• Improves clotting function

• Clinically proven in chronic ITP and liver disease-related thrombocytopenia

• Oral administration for patient convenience

How LITROLAMINE 50 Works

Eltrombopag binds to the thrombopoietin receptor on megakaryocytes, the bone marrow cells responsible for producing platelets. By activating these receptors, it enhances platelet production, helping restore normal platelet levels and reduce the risk of bleeding complications.

This mechanism makes LITROLAMINE 50 highly effective for patients who cannot maintain safe platelet counts naturally or through other treatments.

Uses of LITROLAMINE 50 Tablets

LITROLAMINE 50 is prescribed for:

1. Chronic Immune Thrombocytopenic Purpura (ITP)

   • Helps increase platelet counts in adults who have not responded to other therapies, such as corticosteroids or immunoglobulins.

2. Thrombocytopenia in Chronic Liver Disease

   • Supports patients with liver disease who have low platelet counts prior to procedures or surgeries.

3. Other Low Platelet Conditions

   • Occasionally used in certain bone marrow disorders or secondary thrombocytopenia under specialist supervision.

Benefits of LITROLAMINE 50

• Increases platelet count effectively

• Reduces risk of spontaneous bleeding and bruising

• Enhances quality of life by lowering hospitalization and complication risk

• Convenient oral administration

• Supports long-term management of chronic low platelet disorders

Who Should Take LITROLAMINE 50?

LITROLAMINE 50 is recommended for adults diagnosed with:

• Chronic ITP not responding to conventional therapies

• Liver disease-associated thrombocytopenia requiring intervention

• Persistent low platelet count due to other medical conditions

It should only be taken under the supervision of a healthcare professional.

Dosage and Administration

The dosage of LITROLAMINE 50 is individualized according to the patient’s condition and platelet response:

• Typically, one 50 mg tablet once daily is prescribed.

• Take the tablet on an empty stomach, at least 1 hour before or 2 hours after meals containing calcium, dairy, or antacids, which may interfere with absorption.

• Swallow the tablet whole with water.

• Regular monitoring of platelet counts is essential to adjust the dose safely.

Note: Never change your dose without consulting your doctor.

Duration of Treatment

The duration of therapy varies depending on the patient’s response:

• Some patients may see improvement in platelet counts within 1–2 weeks.

• Long-term therapy may be necessary for chronic ITP.

• Your doctor will monitor platelet levels regularly to determine the optimal treatment period.

Possible Side Effects

Like all medications, LITROLAMINE 50 may cause side effects. Most are mild and temporary, but patients should be aware of potential adverse effects.

Common Side Effects

• Headache

• Nausea or vomiting

• Fatigue

• Dizziness

Less Common Side Effects

• Abdominal discomfort

• Muscle or joint pain

• Mild skin rashes

Rare but Serious Side Effects

• Liver enzyme abnormalities

• Vision disturbances

• Severe bleeding despite therapy

• Blood clots (thrombosis)

Immediate medical attention should be sought if serious side effects occur.

Precautions and Warnings

• Do not use if allergic to Eltrombopag Olamine.

• Patients with liver disease should be closely monitored.

• Regular blood tests are essential to monitor platelet count and liver function.

• Avoid self-medication or dose changes.

• Inform your doctor of other medications, supplements, or herbal remedies.

Pregnancy and Breastfeeding:

• Safety during pregnancy has not been established. Use only if clearly indicated by a doctor.

• Breastfeeding women should consult their healthcare provider before use.

Drug Interactions

LITROLAMINE 50 may interact with:

• Antacids or calcium supplements – reduce absorption

• Blood thinners – increased bleeding risk

• Certain antiviral or antifungal drugs – may affect liver metabolism

• Other platelet-affecting medications – may lead to excessive platelet increase

Always inform your healthcare provider about all medications you are taking.

Lifestyle Tips for Patients with Low Platelets

Alongside medication, healthy habits help maintain platelet health and reduce complications:

• Eat a balanced diet rich in iron, folate, and vitamin B12

• Avoid alcohol and smoking

• Protect yourself from injuries to prevent bleeding

• Stay hydrated and maintain overall wellness

• Engage in moderate exercise approved by your doctor

Monitoring While on LITROLAMINE 50

• Regular platelet count checks are essential

• Liver function tests may be required periodically

• Monitor for any unusual bleeding or clotting

• Keep a record of any side effects experienced

Regular monitoring ensures safety and optimal effectiveness.

Why Choose LITROLAMINE 50?

• Clinically proven Eltrombopag Olamine formulation

• Convenient oral therapy

• Reliable platelet count improvement

• Improves quality of life for patients with chronic thrombocytopenia

• Manufactured under strict quality standards ensuring safety and efficacy

Conclusion

Low platelet counts can pose serious health risks, including spontaneous bleeding, bruising, and increased susceptibility to complications. LITROLAMINE 50 Tablets, containing Eltrombopag Olamine 50 mg, offer a modern, effective solution to safely increase platelet production, manage chronic ITP, and support liver disease-related thrombocytopenia.

Frequently Asked Questions (FAQs)

How long does it take for LITROLAMINE 50 to work?

Patients may see improvement in platelet counts within 1–2 weeks of starting therapy.

Can LITROLAMINE 50 be taken with food?

It is best taken on an empty stomach. Avoid calcium-rich meals or supplements around the dosing time.

Is LITROLAMINE 50 safe for long-term use?

Yes, under strict medical supervision with regular monitoring.

Can children take LITROLAMINE 50?

It is primarily prescribed for adults. Pediatric use should only be under specialist care.

What should I do if I miss a dose?

Take it as soon as you remember. If it is almost time for the next dose, skip the missed one. Do not double the dose.