KEYPROFEN DT

KEYPROFEN DT is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to relieve moderate to severe pain and inflammation. It contains Ketorolac Tromethamine, a potent analgesic known for its ability to provide rapid pain relief. This formulation is specifically designed as a dispersible tablet, which allows for quick dissolution in water, offering a convenient option for patients who may have difficulty swallowing traditional tablets or capsules.

Mechanism of Action:

Ketorolac Tromethamine, the active ingredient in KEYPROFEN DT, works by inhibiting the production of prostaglandins—chemicals in the body that promote inflammation, pain, and fever. By blocking the enzyme cyclooxygenase (COX-1 and COX-2), Ketorolac reduces inflammation and pain, providing fast-acting relief. It is particularly effective in managing acute pain resulting from surgery, injury, or conditions such as osteoarthritis.

Indications:

KEYPROFEN DT is primarily indicated for the short-term management of moderate to severe pain in conditions like:

• Post-operative pain (following surgeries such as dental or orthopedic procedures)

• Acute musculoskeletal pain (such as sprains and strains)

• Pain due to renal colic or kidney stones

• Acute pain from conditions like arthritis or other inflammatory diseases

It is not intended for long-term pain management due to its potential side effects on the gastrointestinal and renal systems.

Key Benefits:

• Rapid Onset of Action: Due to its dispersible formulation, KEYPROFEN DT dissolves quickly in water, allowing faster absorption and quicker pain relief, typically within 30 minutes to 1 hour.

• Convenient Dosage Form: The dispersible tablet form allows for easier administration, especially for patients who have difficulty swallowing whole tablets or capsules. Simply dissolve in water and drink for immediate relief.

• Effective Pain Relief: Provides robust pain management without the need for stronger narcotic analgesics, reducing the risk of dependence and side effects commonly associated with opioids.

• Anti-inflammatory Action: In addition to relieving pain, KEYPROFEN DT effectively reduces inflammation, offering a dual benefit for conditions like sprains, strains, and post-surgical recovery.

Dosage and Administration:

The typical recommended dosage for adults is:

• Initial Dose: 10 mg, which can be taken every 4 to 6 hours.

• Maximum Daily Dose: 40 mg per day.

It is crucial not to exceed the prescribed dose to minimize the risk of side effects, especially gastrointestinal and renal complications.

For optimal results, dissolve the tablet in approximately 100-150 mL of water and consume immediately. The tablet can also be taken with or without food, depending on individual tolerance.

Important Notes:

• This medication is typically used for short-term treatment (up to 5 days). Prolonged use can increase the risk of adverse effects.

• Always follow your healthcare provider's recommendations for dosage and duration of treatment.

Contraindications:

KEYPROFEN DT should not be used by individuals who have:

• A known allergy or hypersensitivity to Ketorolac or any other NSAID

• Active gastrointestinal bleeding, peptic ulcer, or history of gastrointestinal perforation

• Severe renal impairment or a history of renal disease

• History of asthma, urticaria, or other allergic-type reactions after taking aspirin or NSAIDs

• Pregnant women, especially during the third trimester, and breastfeeding mothers (unless advised by a healthcare professional)

Warnings and Precautions:

• Gastrointestinal Risk: Like other NSAIDs, KEYPROFEN DT can increase the risk of serious gastrointestinal events, including bleeding, ulceration, and perforation. Patients should be monitored for signs of GI distress, especially if used long-term.

• Renal Health: Prolonged use or high doses of Ketorolac can affect kidney function, leading to renal impairment. Kidney function should be assessed regularly, particularly in patients with pre-existing kidney conditions.

• Cardiovascular Risk: Ketorolac may increase the risk of heart attack or stroke, particularly with long-term use or in those with pre-existing cardiovascular conditions.

• Elderly Patients: Older adults may be more susceptible to the side effects of NSAIDs, including kidney dysfunction and gastrointestinal problems.

Side Effects:

Common side effects associated with KEYPROFEN DT may include:

• Nausea or upset stomach

• Headache

• Dizziness

• Swelling or fluid retention

Serious side effects that require immediate medical attention include:

• Signs of gastrointestinal bleeding (e.g., black or bloody stools, persistent stomach pain)

• Shortness of breath, chest pain, or swelling of the legs (indicating potential cardiovascular complications)

• Unexplained weight gain or swelling in the hands/feet

• Decreased urine output or kidney-related issues

Conclusion:

KEYPROFEN DT is a highly effective, fast-acting medication designed to provide relief from moderate to severe pain. Its dispersible tablet formulation makes it easy to administer, offering a convenient option for individuals seeking prompt pain relief. Whether used after surgery or for acute injury-related pain, KEYPROFEN DT helps restore comfort and mobility. Always consult your healthcare provider before starting treatment to ensure it is appropriate for your condition.