GLISITAPTIN M 1000

Managing type 2 diabetes mellitus requires a comprehensive approach that includes healthy lifestyle choices and effective medication. GLISITAPTIN M 1000 is a prescription medicine containing sitagliptin phosphate and metformin hydrochloride, a clinically established combination that helps improve blood sugar control in adults with type 2 diabetes. By combining two medicines with complementary mechanisms of action, this therapy supports better glycemic control when diet and exercise alone are not enough.

Manufactured and marketed by Steris Healthcare Pvt. Ltd., GLISITAPTIN M 1000 is produced in a WHO-GMP-certified manufacturing facility that follows stringent quality standards. The medicine is available as enteric-coated delayed-release tablets in a strip of 15 tablets, offering convenient dosing for eligible patients. It is a prescription-only medicine and should be taken only under the supervision of a qualified healthcare professional.

If you are looking to buy Sitagliptin Phosphate Metformin Hydrochloride Tablets online, GLISITAPTIN M 1000 is a reliable option for long-term blood sugar management as part of a personalized diabetes treatment plan.

What are Sitagliptin Phosphate Metformin Hydrochloride Tablets?

GLISITAPTIN M 1000 combines sitagliptin phosphate, a DPP-4 inhibitor, with metformin hydrochloride, a biguanide antidiabetic medicine. Together, these medicines help regulate blood glucose levels through different but complementary actions.

Sitagliptin enhances the body's natural incretin hormones, which stimulate insulin release after meals and reduce glucose production by the liver. Metformin decreases the amount of glucose produced by the liver, improves insulin sensitivity, and reduces glucose absorption from the digestive tract.

This dual-action approach helps improve overall glycemic control and may reduce HbA1c levels when used alongside a balanced diet, regular physical activity, and ongoing medical supervision.

Uses of Sitagliptin Phosphate Metformin Hydrochloride Tablets

GLISITAPTIN M 1000 may be prescribed for:

• Management of type 2 diabetes mellitus
• Improving blood glucose control
• Reducing HbA1c levels
• Adults who require combination oral antidiabetic therapy
• Supporting diabetes management along with diet and exercise
• Long-term maintenance of healthy blood sugar levels under physician supervision

Note: This medicine is not intended for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

How do sitagliptin phosphate-metformin hydrochloride tablets work?

The two active ingredients work together to improve blood sugar control through different mechanisms.

Sitagliptin phosphate inhibits the DPP-4 enzyme, increasing incretin hormone levels. These hormones help the pancreas release insulin when blood sugar rises after meals while decreasing glucose production by the liver.

Metformin hydrochloride reduces glucose production in the liver, improves the body's sensitivity to insulin, and decreases glucose absorption from the intestines.

By targeting multiple pathways involved in blood sugar regulation, GLISITAPTIN M 1000 provides comprehensive support for adults with type 2 diabetes who require combination therapy.

Benefits of sitagliptin phosphate metformin hydrochloride tablets

When taken as prescribed, GLISITAPTIN M 1000 may offer several benefits:

• Helps improve blood sugar control
• Supports reduction of HbA1c levels
• Combines two established diabetes medicines in one tablet
• Improves insulin utilization by the body
• Helps reduce excess glucose production by the liver
• Supports long-term diabetes management
• Convenient tablet formulation
• Manufactured in a WHO-GMP-certified facility

Dosage and Administration

Always take GLISITAPTIN M 1000 exactly as directed by your healthcare provider.

General recommendations include:

• Swallow the tablet whole with water.
• Do not crush, chew, or break the enteric-coated delayed-release tablet unless advised by your doctor.
• Take the medicine with food if recommended to reduce stomach discomfort.
• Take it at the same time each day for consistent blood sugar management.
• Continue following your prescribed diabetic meal plan and exercise routine.
• Monitor blood glucose levels regularly according to your physician's advice.

Never adjust the dose or stop treatment without consulting your healthcare provider.

Possible Side Effects

Like all medicines, GLISITAPTIN M 1000 may cause side effects, although not everyone experiences them.

Common side effects include:

• Nausea
• Diarrhea
• Stomach discomfort
• Loss of appetite
• Headache
• Upper respiratory tract infection
• Nasal congestion
• Mild weakness
• Metallic taste in the mouth

Seek immediate medical attention if you experience severe allergic reactions, persistent vomiting, severe abdominal pain, breathing difficulty, or symptoms suggestive of lactic acidosis or pancreatitis.

Precautions and Warnings

Before taking GLISITAPTIN M 1000, tell your doctor if you have the following:

• Kidney disease
• Liver disease
• Heart disease
• History of pancreatitis
• Vitamin B12 deficiency
• Severe dehydration
• Metabolic acidosis
• Excessive alcohol consumption
• Allergy to Sitagliptin, Metformin, or any tablet ingredients

Pregnant or breastfeeding women should use this medicine only if prescribed by a qualified healthcare professional. Your doctor may recommend periodic monitoring of kidney function, liver function, vitamin B12 levels, and blood glucose during treatment.

Drug Interactions

Inform your doctor about all prescription medicines, over-the-counter drugs, vitamins, and herbal supplements you are taking. Possible interactions include:

• Insulin
• Sulfonylureas
• Corticosteroids
• Diuretics
• ACE inhibitors
• Cimetidine
• Certain contrast dyes used for imaging procedures
• Alcohol
• Other oral antidiabetic medicines

Your healthcare provider may adjust your treatment plan to minimize potential interactions and reduce the risk of side effects.

Storage Instructions

Store GLISITAPTIN M 1000:

• Below 30°C
• In a cool and dry place
• Away from moisture and direct sunlight
• In its original packaging
• Out of reach of children and pets

Do not use the tablets after the expiry date mentioned on the packaging.

Why choose sitagliptin phosphate-metformin hydrochloride tablets?

GLISITAPTIN M 1000 combines sitagliptin phosphate and metformin hydrochloride in one convenient tablet, making it suitable for adults who require combination therapy for type 2 diabetes. Manufactured by Steris Healthcare Pvt. Ltd. in a WHO-GMP-certified facility, it is produced according to stringent quality standards. When taken as prescribed alongside healthy eating, regular exercise, and routine medical monitoring, GLISITAPTIN M 1000 supports effective long-term blood sugar management.

Frequently Asked Questions 

1. What are Sitagliptin Phosphate Metformin Hydrochloride Tablets used for?

These tablets are prescribed to improve blood sugar control in adults with type 2 diabetes mellitus, along with diet and exercise.

2. How do sitagliptin phosphate-metformin hydrochloride tablets work?

It combines sitagliptin, which increases insulin release after meals and reduces glucose production, with metformin, which lowers liver glucose production and improves insulin sensitivity.

3. Can sitagliptin phosphate-metformin hydrochloride tablets be used for type 1 diabetes?

No. This medicine is intended only for adults with type 2 diabetes and is not approved for the treatment of type 1 diabetes or diabetic ketoacidosis.

4. Should I take sitagliptin phosphate and metformin hydrochloride tablets with food?

Your doctor may recommend taking it with meals to reduce stomach-related side effects associated with metformin.

5. What are the common side effects of Sitagliptin Phosphate-Metformin Hydrochloride Tablets?

Common side effects include nausea, diarrhea, stomach upset, headache, upper respiratory infections, and reduced appetite. Contact your doctor if symptoms persist or become severe.

6. Can sitagliptin phosphate metformin hydrochloride tablets be taken with insulin?

Yes, in some cases your doctor may prescribe it with insulin or other diabetes medicines. Your treatment plan will depend on your individual medical needs and blood glucose control.

7. How should I store sitagliptin phosphate-metformin hydrochloride tablets?

Store the tablets below 30°C in a cool, dry place, protected from moisture and sunlight, and keep them out of the reach of children.

8. Do I need a prescription to buy sitagliptin phosphate/metformin hydrochloride tablets?

Yes. GLISITAPTIN M 1000 is a prescription-only medicine and should be purchased and used only under the supervision of a qualified healthcare professional.

Product Specifications