ETOSELECT 400

ETOSELECT 400 is a prescription tablet containing etodolac 400 mg, a non-steroidal anti-inflammatory drug (NSAID) from Steris Healthcare Pvt. Ltd. Doctors in India prescribe etodolac 400 to relieve pain, stiffness and swelling in osteoarthritis and rheumatoid arthritis, and for short-term relief of acute pain such as sprains, strains and post-procedure discomfort. It is not a steroid and not a muscle relaxant. It works by reducing the body's production of prostaglandins, the chemicals that drive pain and inflammation. 

Quick facts	Details
Brand	ETOSELECT 400
Active ingredient	Etodolac 400 mg
Form	Tablet
Pack size	10 tablets
Class	NSAID (preferential COX-2 inhibitor)
Marketed by	Steris Healthcare Pvt. Ltd.
Prescription status	Schedule H – prescription only

What Is ETOSELECT 400 and What Is Etodolac 400 Used For?

ETOSELECT 400 is a branded etodolac 400 mg tablet. Etodolac belongs to the NSAID family, the same broad group as diclofenac, naproxen and ibuprofen. What sets etodolac apart is that it is described as a preferential COX-2 inhibitor: it blocks the COX-2 enzyme (heavily involved in inflammation) more than the COX-1 enzyme (which helps protect the stomach lining). In practice this can mean a somewhat different stomach-tolerability profile compared with older NSAIDs, although it does not remove stomach and heart risks.

Doctors typically consider etodolac 400 for:

Clinical indication	How etodolac helps
Osteoarthritis (knee, hip, hand)	Reduces joint pain, stiffness and swelling so movement is more comfortable
Rheumatoid arthritis	Eases pain and morning stiffness as part of a wider treatment plan
Acute pain (sprains, strains, soft-tissue injury)	Short-term relief of pain and inflammation
Post-procedure or dental pain	Short-term analgesia when an NSAID is appropriate
Other inflammatory musculoskeletal pain	As judged by the treating physician

How Does Etodolac Work? 

When tissue is injured or inflamed, the body converts arachidonic acid into prostaglandins using the cyclo-oxygenase (COX) enzymes. Prostaglandins cause pain, swelling, redness and warmth.

1. Etodolac blocks COX enzymes, with a preference for COX-2, which is upregulated at sites of inflammation.
2. Prostaglandin production falls, so pain signals and swelling reduce.
3. Comfort and mobility improve, which is especially valuable in arthritis, where stiffness limits daily activity.

Key Benefits of ETOSELECT 400

• Targeted anti-inflammatory action: addresses swelling and stiffness, not just pain.
• Convenient 400 mg strength: a single-tablet option that doctors may prescribe once or twice a day depending on the condition.
• Useful for chronic and acute needs: from long-term arthritis care to short courses after an injury.
• Preferential COX-2 selectivity: may offer a different gastrointestinal tolerability profile than non-selective NSAIDs for some patients (individual response varies).
• Quality-backed manufacturing: made by Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical manufacturer in India.

Dosage and How to Take ETOSELECT 400

• Swallow the tablet whole with a full glass of water.
• Take it with or after food or milk to reduce stomach upset.
• Use the lowest effective dose for the shortest duration that controls your symptoms.
• Do not take it together with other NSAIDs or aspirin-containing pain relievers unless your doctor says so.
• If you miss a dose, take it when you remember unless it is almost time for the next one. Never double up.
• Do not lie down for about 10 minutes after taking the tablet if you are prone to acid reflux.

Side Effects of Etodolac 400

Common side effects

• Indigestion, heartburn, stomach pain, nausea
• Gas, bloating, diarrhoea or constipation
• Headache and dizziness
• Mild swelling of feet or ankles (fluid retention)
• Skin rash or itching

Serious side effects – seek urgent medical help

• Black, tarry stools or vomiting blood (stomach or intestinal bleeding)
• Chest pain, breathlessness, weakness on one side of the body or slurred speech (heart attack or stroke risk with NSAIDs)
• Marked reduction in urine, sudden weight gain or severe swelling (kidney problems)
• Yellowing of skin or eyes, dark urine (liver problems)
• Swelling of face, lips or throat, wheezing, severe rash or blistering skin (serious allergic or skin reactions)

Who Should Not Take ETOSELECT 400?

Do not use etodolac if you:

• Are allergic to etodolac, aspirin or any other NSAID (including if aspirin or NSAIDs have triggered asthma, hives or nasal polyps)
• Have an active stomach or intestinal ulcer or bleeding
• Have severe heart failure, severe kidney disease or severe liver disease
• Are in the third trimester of pregnancy
• Are about to have, or recently had, coronary artery bypass graft (CABG) surgery

Tell your doctor before starting if you:

• Have high blood pressure, heart disease, or a past stroke
• Have kidney or liver problems, or are dehydrated
• Have a history of ulcers, gastritis or acid reflux
• Have asthma
• Are pregnant, planning pregnancy, or breastfeeding
• Are elderly (older adults are more sensitive to NSAID side effects)
• Take blood thinners (warfarin), steroids, SSRIs, diuretics, ACE inhibitors or ARBs, lithium, methotrexate or ciclosporin

Other practical points

• Limit alcohol; it raises the risk of stomach irritation.
• Etodolac may cause dizziness in some people. Avoid driving until you know how it affects you.
• Stop the medicine and call your doctor if you notice any warning sign listed above.

ETOSELECT 400 vs Other Pain-Relief Options 

This comparison is educational. Never switch medicines without your doctor's advice.

Medicine (class)	Typical use	Key consideration
Etodolac 400 mg (preferential COX-2 NSAID)	Osteoarthritis, rheumatoid arthritis, acute pain	Take with food; caution in kidney, heart and stomach conditions
Etoricoxib (selective COX-2 inhibitor)	Arthritis, gout, acute pain	Blood pressure monitoring is important
Aceclofenac (NSAID)	Arthritis, musculoskeletal pain	Commonly combined with other agents; stomach caution
Diclofenac (non-selective NSAID)	Pain, inflammation	Stomach and cardiovascular cautions
Naproxen (non-selective NSAID)	Arthritis, period pain, acute pain	Longer-acting; stomach caution
Paracetamol (analgesic)	Mild pain, fever	Pain relief without anti-inflammatory effect

Why choose ETOSELECT 400 from Steris Healthcare?

• Manufactured by a WHO-GMP and ISO-certified company
• Clear labelling of composition, batch number and expiry date
• Reliable supply for pharmacies, hospitals and distributors across India
• Genuine product sourcing directly from the manufacturer's channel

Storage and Safe Handling

• Keep the strip in its original pack until use.
• Store away from heat, moisture and direct light.
• Do not use after the expiry date printed on the strip.
• Never share your prescription medicines with anyone else.

Conclusion

ETOSELECT 400 (etodolac 400 mg) is a well-established anti-inflammatory option for managing the pain, stiffness and swelling of osteoarthritis and rheumatoid arthritis, and for short-term relief of acute pain. Used correctly, with food, at the lowest effective dose and under medical supervision, it can help restore comfortable movement. Like all NSAIDs, it carries stomach, heart and kidney risks, so regular review with your doctor matters. If your doctor has prescribed it, you can check the price of ETOSELECT 400 through Steris Healthcare.

Frequently Asked Questions 

1. What is etodolac 400 used for?

Etodolac 400 mg is used to relieve pain, stiffness and swelling in osteoarthritis and rheumatoid arthritis, and for short-term treatment of acute pain such as sprains, strains and post-procedure pain. It is an NSAID that reduces the prostaglandins responsible for inflammation. It treats symptoms rather than curing the underlying joint disease, and it should only be taken on a doctor's prescription.

2. Is etodolac a steroid tablet?

No. Etodolac is not a steroid. It is a non-steroidal anti-inflammatory drug (NSAID). Steroids such as prednisolone or dexamethasone are hormone-like medicines, whereas etodolac works by blocking COX enzymes to reduce pain and inflammation. This means it does not carry steroid-specific effects, but it still has its own NSAID risks.

3. Can I take etodolac every day?

Some people with chronic arthritis are prescribed etodolac daily, but only under medical supervision. Long-term NSAID use increases the risk of stomach ulcers, raised blood pressure, kidney problems and cardiovascular events, so doctors aim for the lowest effective dose for the shortest time. Do not self-medicate daily, and have regular check-ups if you are on it long term.

4. Is etodolac safe for kidneys?

Etodolac, like all NSAIDs, can reduce blood flow to the kidneys and may harm kidney function, especially in people who are dehydrated, elderly, or have existing kidney disease, heart failure or liver disease, or who take diuretics or ACE inhibitors/ARBs. It is generally avoided in severe kidney disease. Tell your doctor about any kidney problem before starting, and drink adequate fluids as advised.

5. Will etodolac make me sleepy?

Etodolac is not a sedative, and drowsiness is not its main effect. However, some people report dizziness, tiredness or light-headedness. Until you know how it affects you, avoid driving or operating machinery. If you feel unusually sleepy or dizzy, speak to your doctor.

6. Can I take 2 etodolac 400 mg?

Do not take two tablets (800 mg) unless your doctor has specifically told you to. Taking more than prescribed increases the risk of stomach bleeding, kidney injury and heart problems. The right dose and the maximum daily limit depend on your condition and health, so follow your prescription exactly. If you have taken extra by mistake, contact your doctor or a poison control centre promptly.

7. Is etodolac a muscle relaxer?

No. Etodolac is an anti-inflammatory pain reliever, not a muscle relaxant. It can ease pain from muscle and joint injuries by reducing inflammation, but it does not relax muscle spasm directly. If spasm is the main problem, doctors sometimes prescribe a separate muscle relaxant alongside an NSAID.

8. What is the price of etodolac 400 mg tablet in India?

The price depends on the brand, pack size and seller. ETOSELECT 400 is available as a pack of 10 tablets. For the current MRP, use the Check Price link on the Steris Healthcare product page, and always buy against a valid prescription.

9. Do I need a prescription to buy ETOSELECT 400?

Yes. ETOSELECT 400 is a Schedule H drug, which means it can be sold only against a valid prescription from a registered medical practitioner.

10. Should I take ETOSELECT 400 before or after food?

Take it with or after food or milk. This helps reduce stomach irritation, nausea and acidity. Swallow the tablet whole with water.

11. What are the common side effects of etodolac 400 mg?

Common side effects include indigestion, stomach pain, nausea, gas, diarrhoea or constipation, headache, dizziness, mild ankle swelling and skin rash. Most are mild, but if you notice black stools, vomiting blood, chest pain or severe rash, seek emergency care.

12. Can I take etodolac with paracetamol or other painkillers?

Doctors sometimes combine an NSAID with paracetamol for better pain control. However, you should not combine etodolac with another NSAID (such as diclofenac, ibuprofen or aspirin for pain) because it raises the risk of side effects. Always check with your doctor or pharmacist first.

13. Can etodolac be taken during pregnancy or breastfeeding?

NSAIDs should generally be avoided in pregnancy, and etodolac is not recommended in the third trimester because it may affect the baby's circulation and cause complications. Discuss with your doctor if you are pregnant, planning pregnancy, or breastfeeding before using it.

14. Does etodolac raise blood pressure or affect the heart?

NSAIDs can cause fluid retention and raise blood pressure, and they carry a warning about increased risk of heart attack and stroke, particularly with higher doses and long-term use. People with heart disease or high blood pressure should use etodolac only under close medical supervision.

15. Can I drink alcohol while taking etodolac 400?

It is best to avoid or strictly limit alcohol. Alcohol combined with NSAIDs increases the risk of stomach irritation and bleeding.

16. How long does etodolac take to work?

Many people notice pain relief within a few hours of a dose, while the full anti-inflammatory benefit in arthritis may take longer with regular use. Response varies from person to person, so follow your doctor's guidance rather than increasing the dose.

17. Who should avoid ETOSELECT 400?

People allergic to NSAIDs or aspirin, those with active stomach ulcers or bleeding, severe kidney, liver or heart failure, women in the third trimester of pregnancy, and patients around coronary bypass surgery should avoid it. Elderly patients and those taking blood thinners need extra caution.

18. Where can I order ETOSELECT 400 online in India?

You can check the price and enquire through the Steris Healthcare product page on sterisonline.com with a valid prescription. Pharmacies and distributors can also contact the Steris team using the details below.