DOBELATE PLUS

Dobelate Plus is a thoughtfully formulated combination tablet that brings together three complementary vascular-supportive ingredients: Citrus Bioflavonoids, Vitamin C, and Calcium Dobesilate. This combination is designed specifically to target conditions arising from weakened or fragile blood vessel walls, a common underlying factor in several everyday vascular and venous health complaints.

Manufactured by Steris Healthcare, a WHO-GMP and ISO 9001:2018 certified pharmaceutical company, this tablet is prescribed by general physicians, gastroenterologists, and vascular specialists for patients experiencing symptoms related to capillary fragility and impaired venous tone.

Product Information

Why It's Important

Vascular fragility and impaired venous tone underlie a surprisingly wide range of common health complaints — from hemorrhoids and varicose veins to easy bruising and chronic venous insufficiency. These conditions, while rarely life-threatening, can significantly affect daily comfort, mobility, and quality of life, particularly for individuals who spend long hours standing or sitting, women during pregnancy, or those with a family history of venous disease.

The clinical importance of a combination product like Dobelate Plus lies in how it addresses the vascular root cause rather than symptoms alone. Calcium Dobesilate is well recognized for its venotonic properties, helping to reduce capillary permeability and improve microcirculatory blood flow. Citrus Bioflavonoids, naturally occurring plant compounds found in citrus fruits, have long been valued for their role in supporting vascular wall strength and reducing capillary fragility. Vitamin C complements this action by supporting collagen synthesis, an essential structural component of healthy blood vessel walls, while also contributing antioxidant support to protect vascular tissue from oxidative stress.

Together, these three ingredients offer a rational, multi-angle approach to supporting vascular health — particularly relevant in India, where lifestyle factors such as prolonged sitting, low-fiber diets contributing to constipation and hemorrhoidal strain, and genetic predisposition to venous insufficiency are widespread contributors to these conditions. For many patients, incorporating a vascular-supportive tablet alongside dietary and lifestyle changes can meaningfully improve symptom control and reduce the frequency of flare-ups.

Key Benefits 

What Are the Benefits of Dobelate Plus?

Citrus Bioflavonoids, Vitamin C & Calcium Dobesilate, as combined in Dobelate Plus, offers several clinically meaningful advantages:

• Improved vascular wall integrity: The combination of Citrus Bioflavonoids and Vitamin C supports collagen synthesis and structural strength in blood vessel walls, helping reduce capillary fragility.
• Reduced capillary permeability: Calcium Dobesilate's venotonic action helps reduce excessive permeability in small blood vessels, which can contribute to swelling and minor bleeding tendencies.
• Support for hemorrhoidal symptom management: By strengthening vascular tone in the anorectal region, this combination can help reduce bleeding tendency and discomfort associated with hemorrhoids.
• Relief from varicose vein-related discomfort: Many patients experience reduced heaviness, aching, and swelling in the legs with consistent use as part of a broader management plan.
• Reduced tendency for easy bruising: By supporting capillary strength, this combination may help reduce the frequency of minor bruising in individuals prone to vascular fragility.
• Antioxidant support: Vitamin C contributes additional antioxidant protection, helping shield vascular tissue from oxidative stress that can further weaken blood vessel walls over time.
• Convenient oral tablet form: Unlike topical treatments that address only localized symptoms, this oral combination offers systemic vascular support throughout the body.
• Trusted manufacturing standards: Dobelate Plus is manufactured by Steris Healthcare, a WHO-GMP and ISO 9001:2018 certified pharmaceutical company, ensuring consistent ingredient concentration and reliable quality across every batch.

Side Effects 

Dobelate Plus is generally well tolerated, as its components are widely used and have a favorable safety profile. However, some patients may experience mild side effects, including:

• Mild gastrointestinal discomfort, such as nausea or stomach upset, particularly if taken on an empty stomach
• Diarrhea, particularly with higher Vitamin C intake
• Mild headache
• Occasional dizziness
• Mild skin flushing in sensitive individuals

Most of these effects are mild and transient, and can often be minimized by taking the tablet with food and adequate water.

Precautions & Warnings

Before starting Dobelate Plus, patients and prescribers should consider the following precautions:

• Kidney Stone History: Patients with a history of kidney stones, particularly oxalate stones, should discuss Vitamin C intake with their physician, as high doses may theoretically increase stone risk in predisposed individuals.
• Renal Impairment: Caution is advised in patients with significant kidney dysfunction, given the renal excretion of some components.
• Pregnancy and Breastfeeding: Should be used only under medical guidance during pregnancy and breastfeeding, with appropriate risk-benefit assessment by the treating physician.
• Persistent or Heavy Bleeding: Any significant or persistent bleeding, whether rectal or otherwise, should be promptly evaluated by a physician rather than managed solely with this combination.
• Diabetes: Patients with diabetes should be aware that some formulations may contain excipients relevant to blood sugar management; product labeling should be checked or discussed with a pharmacist.
• Drug Interactions: Vitamin C in high doses may interact with certain medications, including some chemotherapy agents and anticoagulants; all current medications should be disclosed to the prescribing physician.
• Underlying Cause Management: This combination supports vascular health but does not replace the need to address underlying contributing factors, such as chronic constipation, prolonged standing, or other vascular risk factors, as guided by a physician.

Mechanism of Action

Dobelate Plus works through the combined, complementary action of its three active components:

1. Calcium Dobesilate: This component acts primarily as a venotonic and vascular-protective agent, reducing capillary permeability and fragility. It works by decreasing the hyperpermeability of small blood vessels, improving microcirculatory function, and reducing platelet hyperaggregability, which collectively help reduce swelling, bleeding tendency, and discomfort associated with vascular fragility.
2. Citrus Bioflavonoids: These naturally derived plant compounds contribute antioxidant and vascular-protective properties, helping to strengthen capillary walls and reduce their permeability. They are believed to work synergistically with Vitamin C to support overall vascular tissue integrity.
3. Vitamin C (Ascorbic Acid): As an essential cofactor in collagen synthesis, Vitamin C supports the structural integrity of blood vessel walls, which are rich in collagen. Its antioxidant properties additionally help protect vascular tissue from oxidative damage that can otherwise weaken vessel walls over time.

Together, these three mechanisms — reduced capillary permeability, strengthened vascular collagen structure, and antioxidant protection — provide a comprehensive, multi-angle approach to supporting vascular health, explaining the combination's relevance across hemorrhoidal disease, varicose veins, and general capillary fragility.

Frequently Asked Questions

1. Where can I buy Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate online?
You can buy Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate from licensed online pharmacies or authorized pharmaceutical suppliers, subject to availability.

2. What is the price of Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate?
The price may vary depending on the brand, pack size, seller, and applicable offers. Check the current listed price before ordering.

3. Can I order Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate online?
Yes, the product may be ordered online through licensed pharmacies or authorized suppliers, subject to availability and applicable requirements.

4. Is Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate available from Steris Healthcare?
Availability depends on Steris Healthcare's current product range and stock status. Contact Steris Healthcare or an authorized distributor for current availability.

5. What is Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate used for?
This combination may be used to support vascular health and manage certain conditions involving blood vessels and circulation, as directed by a healthcare professional.

6. What is the composition of Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate?
The composition includes Citrus Bioflavonoids, Vitamin C, and Calcium Dobesilate. The exact strength of each ingredient depends on the specific formulation.

7. Is a prescription required?
Prescription requirements may vary depending on the formulation and local regulations. Follow the advice of a qualified healthcare professional.

8. How should Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate be taken?
Take the tablets orally exactly as directed by your healthcare professional. Do not change the dose or duration without medical advice.

9. What should I know before buying Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate?
Check the composition, strength, pack size, expiry date, storage instructions, and seller authenticity. Inform your healthcare professional about allergies, medical conditions, pregnancy, or other medicines you use.

10. How can I order Citrus Bioflavonoids, Vitamin C Tablets & Calcium Dobesilate online?
Select the required product and pack size from a licensed pharmacy or authorized supplier, verify any prescription requirements, and complete the available payment and delivery process.