Bosentan 62.5 mg | BOSENTIME 62.5

Bosentan 62.5  is a Prescription-only bosentan treats PAH by widening lung blood vessels, lowering pulmonary blood pressure and improving exercise capacity. It is manufactured and marketed in India by Steris Healthcare Pvt. Ltd. A doctor usually starts bosentan 62.5 mg twice daily for the first 4 weeks, then reviews the dose. Regular liver function tests and pregnancy testing (for women who can become pregnant) are essential. Bosentan is a 

Product Information: BOSENTIME 62.5

What Is Bosentan 62.5 Used For?

Bosentan 62.5 is prescribed by pulmonologists, cardiologists and PAH specialists to manage pulmonary arterial hypertension. In PAH, the small arteries in the lungs narrow and thicken, forcing the right side of the heart to work harder. Over time this causes breathlessness, fatigue, dizziness, chest discomfort and reduced exercise capacity.

How Does Bosentan 62.5 Work? 

Endothelin-1 is a natural substance in the body that constricts blood vessels and encourages the abnormal growth of vessel walls. In PAH, endothelin-1 levels are raised. Bosentan is a dual endothelin receptor antagonist: it blocks both ETA and ETB receptors, reducing vasoconstriction and vascular remodelling in the lungs. The result is lower resistance in the pulmonary arteries and less strain on the heart.

Key Benefits of Bosentan 62.5

• Targets the disease pathway: it acts on endothelin signalling, a key driver of PAH, rather than only relieving symptoms.
• Oral therapy: it is taken as a tablet, twice daily.
• Flexible starting strength: the 62.5 mg strength allows the structured starting dose and lower-weight dosing that doctors commonly use.
• Works with other PAH treatments: specialists sometimes combine it with other PAH medicines, always with careful interaction checks.
• Made in India to quality standards: BOSENTIME 62.5 is produced by a WHO-GMP and ISO-certified manufacturer.

Dosage and How to Take Bosentan 62.5

• Starting dose: bosentan 62.5 mg twice daily (morning and evening) for the first 4 weeks.
• Maintenance dose: commonly increased to 125 mg twice daily if tolerated. Patients under 40 kg may continue at 62.5 mg twice daily.
• Timing: take it at the same times each day, with or without food, and swallow it with water.
• Duration: PAH is a long-term condition, so treatment is usually continued as long as the specialist advises.

Side Effects of Bosentan 62.5

Common side effects

• Headache
• Flushing
• Nasal congestion or sore throat
• Swelling of the ankles or legs (fluid retention)
• Abnormal liver blood tests
• Indigestion or nausea
• Fatigue and itching

Serious side effects (seek medical help promptly)

• Signs of liver injury: yellow skin or eyes, dark urine, upper-right abdominal pain, unusual tiredness, persistent nausea or vomiting
• Symptoms of anaemia: marked weakness, pale skin, breathlessness
• Rapid weight gain or worsening swelling and breathlessness
• Severe allergic reaction: rash, facial swelling, difficulty breathing

Precautions and Safety: What to Know Before Buying Bosentan 62.5

1. Pregnancy: bosentan can cause serious birth defects. Women who can become pregnant need a negative pregnancy test before starting and regularly during treatment, plus reliable contraception as advised by the doctor. Hormonal contraceptives alone may not be enough.
2. Liver monitoring: liver function tests are done before starting and regularly during treatment, usually monthly.
3. Anaemia: haemoglobin is checked at the start and at intervals during treatment.
4. Who should not use it: people with moderate-to-severe liver impairment, those who are pregnant, and those taking cyclosporine or glibenclamide (glyburide).
5. Drug interactions: tell your doctor about all medicines you take, including rifampicin, ketoconazole, ritonavir, sildenafil, warfarin, statins, tacrolimus and hormonal contraceptives.
6. Male fertility: bosentan may reduce sperm count, so discuss this with your doctor if you plan a family.
7. Breastfeeding: not recommended during treatment. Speak to your doctor.
8. Dizziness: bosentan may lower blood pressure, so be careful when driving or operating machinery until you know how it affects you.

 How to Check Price and Order BOSENTIME 62.5 in India

Because bosentan is a Schedule H medicine, it can only be dispensed against a valid prescription. To check the price and availability of BOSENTIME 62.5 from Steris Healthcare:

1. Keep your prescription ready: it should be from a registered medical practitioner and mention bosentan 62.5 mg and the dose.
2. Contact Steris Healthcare: use the phone numbers or emails below.
3. Share the details: give the brand (BOSENTIME 62.5), pack size, quantity and delivery location in India.
4. Confirm price and availability: the team will confirm current MRP, stock and dispatch options.
5. Verify on delivery: check the brand name, batch number, expiry date and sealed pack.

Why Choose BOSENTIME 62.5 from Steris Healthcare?

• Trusted manufacturing: Steris Healthcare Pvt. Ltd. is a WHO-GMP and ISO-certified pharmaceutical manufacturer based in India.
• Focused product information: clear composition, strength and usage details to support informed conversations with your doctor.
• Direct enquiry support: price and availability confirmed by the manufacturer/marketer.
• Quality-first approach: each batch is manufactured to regulated standards.

Conclusion

Bosentan 62.5 (BOSENTIME 62.5) is an endothelin receptor antagonist for pulmonary arterial hypertension, a condition that needs specialist care, regular monitoring and consistent treatment. Its benefit depends on correct dosing, timely liver and blood tests, pregnancy precautions where relevant, and a full review of your other medicines. If your doctor has prescribed bosentan 62.5 mg, contact Steris Healthcare to check price and availability.

Frequently Asked Questions 

1. Where can I buy bosentan 62.5 online?
Bosentan 62.5 is a Schedule H medicine, so it should be obtained only with a valid prescription from a licensed source. You can enquire about BOSENTIME 62.5
The price of bosentan 62.5 depends on the brand, pack size and supplier, and can change over time. For the current MRP of BOSENTIME 62.5, use "Check Price" and contact Steris Healthcare on the numbers above. [MRP – confirm with Steris Healthcare before publishing.]

3. Can I order bosentan 62.5 online?
Yes, you can send an order enquiry online, but you must have a valid prescription because bosentan is a prescription-only drug. Share the prescription, the required quantity and your delivery location in India with Steris Healthcare to confirm availability and price.

4. Is bosentan 62.5 available from Steris Healthcare?
Steris Healthcare Pvt. Ltd. is the manufacturer and marketer of BOSENTIME 62.5 (Bosentan 62.5 mg). Stock and dispatch timelines can vary, so please contact the team on +91 8824175417 or +91 9982524671, or by email, to confirm availability.

5. What is bosentan 62.5 used for?
Bosentan 62.5 is used to treat pulmonary arterial hypertension (PAH), high blood pressure in the lung arteries that causes breathlessness, tiredness and reduced exercise capacity. In some settings, specialists may also use it to reduce new digital ulcers in systemic sclerosis. It is prescribed only by a doctor.

6. What is the composition of bosentan 62.5?
Each BOSENTIME 62.5 tablet contains Bosentan 62.5 mg, an endothelin receptor antagonist. Inactive ingredients vary by formulation, so check the pack label if you have known allergies.

7. Is a prescription required for bosentan 62.5?
Yes. Bosentan is a Schedule H drug and requires a prescription from a registered medical practitioner. It needs supervised use and regular liver and blood tests, so it should never be self-medicated.

8. How should bosentan 62.5 be taken?
Take it exactly as prescribed, usually twice daily, morning and evening, with or without food, and swallowed with water. A common starting dose is bosentan 62.5 mg twice daily for 4 weeks, after which the doctor may adjust it. Do not change the dose or stop without medical advice.

9. What should I know before buying bosentan 62.5?
Confirm that you have a valid prescription and that the brand, strength (62.5 mg) and pack size match it. Understand the monitoring needs, which are regular liver function tests, haemoglobin checks and pregnancy tests for women who can become pregnant. Tell your doctor about all your medicines, especially cyclosporine, glibenclamide, rifampicin, sildenafil, warfarin and hormonal contraceptives. Buy only from authorised sources and check the sealed pack, batch number and expiry date.

10. How can I order bosentan 62.5 online?
Keep your prescription ready, contact Steris Healthcare by email or phone, and share the brand (BOSENTIME 62.5), quantity, pack size and delivery address. Confirm the price and dispatch details, then verify the pack on delivery. Prescription only – consult your doctor.

11. What are the side effects of bosentan 62.5?
Common side effects include headache, flushing, nasal congestion, ankle swelling, indigestion, fatigue and abnormal liver test results. Serious effects include liver injury (yellow eyes or skin, dark urine, abdominal pain), anaemia and significant fluid retention. Contact your doctor promptly if you notice these.

12. Why are liver function tests needed with bosentan 62.5?
Bosentan can raise liver enzymes and, in some patients, cause liver injury. Your doctor will check liver function before starting and regularly during treatment, usually every month, so that any change is caught early and the dose can be adjusted or stopped if needed.

13. Can women who may become pregnant take bosentan 62.5?
Bosentan can cause serious harm to an unborn baby and is contraindicated in pregnancy. Women who can become pregnant need a negative pregnancy test before treatment and regular tests during it, along with reliable contraception recommended by the doctor. Hormonal contraceptives alone may not be sufficient.

14. Which medicines interact with bosentan 62.5?
Bosentan should not be combined with cyclosporine or glibenclamide (glyburide). Other medicines such as rifampicin, ketoconazole, ritonavir, sildenafil, warfarin, statins, tacrolimus and hormonal contraceptives can change how bosentan or the other drug works. Always share your full medicine list with your doctor and pharmacist.

15. Can I drink alcohol while taking bosentan 62.5?
Because bosentan can affect the liver, it is best to avoid alcohol or discuss safe limits with your doctor before drinking.

16. What should I do if I miss a dose of bosentan 62.5?
Take it as soon as you remember. If it is almost time for the next dose, skip the missed one and continue your normal schedule. Do not take a double dose.

17. Can I stop bosentan 62.5 suddenly?
No. Stopping suddenly may allow PAH symptoms to worsen. Speak to your doctor first. If a dose reduction or stop is needed, your doctor will guide you.

18. How should bosentan 62.5 be stored?
Store the tablets in the original pack as directed on the label, away from moisture, heat and direct light. Keep them out of the reach of children, and do not use them after the expiry date.