Sitagliptin Phosphate (50mg), Metformin HCI (1000mg) ""

Sitagliptin Phosphate (50mg), Metformin HCI (1000mg)
GLISITAPTIN M 1000  
Sitagliptin phosphate and metformin HCl are both medications used to treat type 2 diabetes. 
Sitagliptin phosphate is a medication classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by inhibiting the enzyme DPP-4, which is responsible for breaking down incretin hormones like GLP-1 (glucagon-like peptide-1). GLP-1 is an incretin hormone that stimulates insulin secretion and reduces glucagon release from the pancreas. By inhibiting DPP-4, sitagliptin increases the levels of GLP-1, which leads to better control of blood sugar levels after meals.
Metformin is a member of the biguanide class of medications. It works primarily by decreasing the production of glucose in the liver and increasing the sensitivity of muscle cells to insulin. This helps improve the uptake of glucose from the bloodstream into cells, reducing blood sugar levels. Metformin also has some effects on the gut and may influence gut bacteria, which can play a role in its overall impact on metabolism.
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