"Sitagliptin 100mg: Comprehensive Diabetes Care"

Introduction

ST-GLIPTIN 100 is an advanced oral anti-diabetic formulation containing Sitagliptin 100 mg, also marketed as sitagliptin phosphate tablets IP 100mg. It is used as part of a comprehensive treatment plan for adults with Type 2 Diabetes Mellitus (T2DM). As a DPP-4 (dipeptidyl peptidase-4) inhibitor, Sitagliptin helps to improve glycemic control by enhancing the body's natural ability to regulate blood sugar levels.This product is manufactured by Steris Healthcare Pvt. Ltd., a company known for its commitment to high-quality and affordable pharmaceutical solutions.

Mechanism of Action

Sitagliptin works by inhibiting the enzyme DPP-4, which degrades incretin hormones such as GLP-1 and GIP. These hormones are responsible for:

• Stimulating insulin release in response to meals

• Reducing glucagon secretion

• Delaying gastric emptying

By preventing the breakdown of incretin hormones, sitagliptin phosphate 100mg enhances the body’s natural insulin response, particularly after meals. It helps lower fasting and postprandial blood glucose levels, offering a glucose-dependent mechanism of action that reduces the risk of hypoglycemia.

Indications

ST-GLIPTIN 100 is indicated for the management of Type 2 Diabetes Mellitus:

• As monotherapy in adults who are not adequately controlled by diet and exercise alone

• In combination with other antidiabetic agents, such as:

  • Metformin

  • Sulfonylureas

  • Thiazolidinediones (e.g., Pioglitazone)

  • Insulin

It is not indicated for Type 1 Diabetes or diabetic ketoacidosis.

Dosage and Administration

• Recommended Dose: One tab. sitagliptin 100mg (Sitagliptin 100 mg) once daily

• Administration: Can be taken with or without food

• Renal Impairment: Dose adjustment required:

  • eGFR ≥45: 100 mg daily

  • eGFR ≥30–<45: 50 mg daily

  • eGFR <30 or ESRD on dialysis: 25 mg daily

Physician supervision is recommended for dosing adjustments.

Clinical Benefits of ST-GLIPTIN 100

• Glucose-Dependent Action – Lowers glucose only when needed, minimizing hypoglycemia
• Weight-Neutral – Unlike other diabetes medications, does not cause weight gain
• Well-Tolerated in Elderly – Safe when renal function is monitored
• Flexible Dosing – Once-daily dose for better compliance
• Synergistic with Other Therapies – Especially effective with Metformin

The use of sitagliptin phosphate tab 100 mg has been proven in various clinical studies for sustained HbA1c reduction.

Side Effects

Most patients tolerate sitagliptin 100mg well. Common side effects include:

• Headache

• Nasopharyngitis (cold-like symptoms)

• Upper respiratory tract infection

• Stomach upset or gas

Rare but serious side effects:

• Pancreatitis

• Severe joint pain

• Allergic reactions (rash, swelling, difficulty breathing)

• Kidney dysfunction (especially in those with pre-existing renal issues)

Drug Interactions

While sitagliptin phosphate tablets ip 100mg has minimal drug interactions, caution should be used with:

• Sulfonylureas or insulin (higher risk of hypoglycemia)

• Digoxin (plasma levels may slightly increase)

Always inform your doctor about all the medications and supplements you are taking.

Precautions and Warnings

• Not for use in Type 1 Diabetes or Diabetic Ketoacidosis (DKA)

• Use with caution in patients with renal impairment

• Not recommended in pregnancy or breastfeeding unless prescribed

• Discontinue if symptoms of pancreatitis appear

• Monitor renal function and HbA1c regularly during therapy

Storage Instructions

• Store at room temperature (below 30°C)

• Keep away from moisture and direct sunlight

• Keep out of reach of children

Product Summary

FAQs – Frequently Asked Questions

1. What is Sitagliptin 100mg used for?

It is used for managing blood sugar levels in adults with Type 2 Diabetes Mellitus.

2. Is Sitagliptin 100mg safe to use long-term?

Yes, clinical studies support the long-term safety and efficacy of sitagliptin phosphate 100mg when used as directed.

3. Can Sitagliptin cause weight gain?

No, it is considered weight-neutral.

4. What if a dose is missed?

Take the missed dose as soon as you remember. Skip it if it’s close to your next dose—do not double dose.

5. Can it be used with insulin?

Yes, but under medical supervision to reduce the risk of hypoglycemia.

Conclusion

ST-GLIPTIN 100 containing Sitagliptin Phosphate Tablets IP 100mg offers a safe, effective, and patient-friendly approach to managing Type 2 Diabetes. It improves glycemic control, works synergistically with other treatments, and carries a low risk of hypoglycemia. Manufactured with stringent quality standards by Steris Healthcare Pvt. Ltd., it provides dependable support for long-term diabetes management.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW