"Manage Type 2 Diabetes with SITAGLIPTIN 50 + METFORMIN 500"

STERIS SITAGLIPTIN 50 + METFORMIN 500 

Sitagliptin (50mg) & Metformin HCI (500mg)

Introduction

Sitagliptin (50mg) and Metformin HCI (500mg) is a combination medication designed to effectively manage type 2 diabetes. This dual-action therapy combines the benefits of Sitagliptin, a DPP-4 inhibitor, and Metformin, a biguanide, to help control blood sugar levels, enhance insulin sensitivity, and improve overall glucose metabolism. STERIS SITAGLIPTIN 50 + METFORMIN 500 offers a comprehensive approach to diabetes care.

Mechanism of Action

Sitagliptin (50mg)

• Sitagliptin works by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme, which breaks down incretin hormones. Incretin hormones play a crucial role in regulating blood sugar levels by increasing insulin synthesis and release from pancreatic beta cells and decreasing glucagon production. By preventing the breakdown of these hormones, Sitagliptin enhances their action, leading to better blood sugar control.

Metformin HCI (500mg)

• Metformin is a biguanide that reduces the amount of glucose produced by the liver and improves the body’s sensitivity to insulin. It helps increase glucose uptake and utilization by cells, thus lowering blood sugar levels. The combination of Metformin's effects ensures prolonged glucose control and improved metabolic function.

Uses

• Type 2 Diabetes Management: This combination is primarily used to manage type 2 diabetes in adults, helping to control blood sugar levels and prevent complications associated with diabetes.
• Postprandial Glucose Control: The combination helps manage post-meal blood sugar spikes, providing more stable glucose levels throughout the day.
• Cardiovascular Health: Effective blood sugar management helps reduce the risk of cardiovascular diseases associated with diabetes.

Dosage and Administration

The typical dosage is one tablet of Sitagliptin (50mg) and Metformin HCI (500mg) taken once daily with the evening meal. This helps to reduce gastrointestinal side effects and ensures optimal absorption. Regular blood sugar monitoring and follow-ups with your healthcare provider are essential to ensure the medication’s effectiveness.

Side Effects

Common side effects include:

• Nausea
• Diarrhea
• Headache
• Upper respiratory tract infections
• Hypoglycemia (low blood sugar)

Serious side effects may include:

• Lactic acidosis (a rare but serious complication of metformin)
• Pancreatitis (from sitagliptin)
• Severe allergic reactions

Precautions

• Kidney Function: Regular monitoring of kidney function is recommended, especially for patients with renal impairment.
• Liver Function: Patients with liver disease should use this combination cautiously.
• Hydration: Ensure adequate hydration to avoid dehydration.

Conclusion

Sitagliptin (50mg) and Metformin HCI (500mg), marketed as STERIS SITAGLIPTIN 50 + METFORMIN 500, offers a comprehensive approach to managing type 2 diabetes. By targeting different aspects of glucose metabolism, this combination helps maintain optimal blood sugar levels and improve overall health. Always follow your healthcare provider’s instructions and attend regular check-ups to ensure safe and effective treatment.Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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