Prochlorperazine MD (5mg) & PROCHLOROMETIL MD :Tablet- View Uses, Side Effects, Dosage, Mechanism of action...

Introduction

Prochlorperazine Maleate is a phenothiazine derivative that acts as both an antiemetic (prevents nausea/vomiting) and a typical antipsychotic. In the MD (mouth-dissolving) form, the tablet dissolves quickly on the tongue, offering faster relief without the need for water—ideal for nausea or vertigo in emergencies or for patients with swallowing difficulties.

Composition of PROCHLOROMETIL MD

Each mouth-dissolving tablet contains:

• Prochlorperazine Maleate IP equivalent to Prochlorperazine 5 mg

• Excipients – q.s.

• Flavour & Sweetener – For palatability

• Form – Rapidly dissolving tablet for oral mucosal absorption

Prochlorperazine Maleate 5 mg Uses

PROCHLOROMETIL MD is indicated for:

• Nausea and Vomiting – Due to various causes (including post-operative, chemotherapy, or motion sickness)

• Vertigo – Including vestibular disorders

• Migraine-associated Nausea

• Psychosis – As a secondary indication in anxiety or schizophrenia

• Severe Morning Sickness (under specialist guidance)

Prochlorperazine acts as a dopamine (D2) receptor antagonist in the chemoreceptor trigger zone (CTZ) and the vomiting center of the brain, which suppresses the nausea reflex. It also has central antipsychotic effects through D2 blockade in mesolimbic pathways.

Key Benefits of PROCHLOROMETIL MD

• Fast action due to oral mucosal absorption

• Convenient for patients with nausea, vomiting, or trouble swallowing

• Dual action: Antiemetic + mild antipsychotic/anxiolytic

• Available in 5 mg strength for flexible dosing

• No water required – ideal for travel/emergency use

Dosage and Administration

Usual Adult Dosage:

• Antiemetic use: 5–10 mg 2–3 times daily

• Vertigo/migraine-related nausea: 5 mg every 8 hours as needed

• In elderly or debilitated: Start at lower doses

 How to Take: Place one tablet on the tongue and allow it to dissolve completely. Do not swallow or chew.

Side Effects of Prochlorperazine Maleate

Common Side Effects:

• Drowsiness or sedation

• Dry mouth

• Dizziness

• Blurred vision

• Constipation

Serious (Less Common) Side Effects:

• Extrapyramidal symptoms (tremor, rigidity)

• Tardive dyskinesia (in long-term use)

• Hypotension

• Neuroleptic malignant syndrome (rare)

• Allergic reactions

Warnings and Precautions

• Avoid alcohol and CNS depressants

• Use with caution in elderly (risk of falls, sedation)

• Not recommended in children <2 years

• Use cautiously in Parkinson’s disease, epilepsy, or cardiovascular conditions

Drug Interactions

• Enhanced sedation with benzodiazepines, opioids

• May reduce effect of levodopa

• Risk of QT prolongation with macrolides or fluoroquinolones

Storage Instructions

• Store at room temperature (15–25°C)

• Keep in a dry place, away from sunlight and moisture

• Use the product within the expiry date printed on the blister

• Keep out of reach of children

Frequently Asked Questions (FAQs)

1. What is PROCHLOROMETIL MD used for?

It is used to prevent or treat nausea and vomiting, especially in cases of motion sickness, post-surgery, or vertigo.

2. Is it safe to use PROCHLOROMETIL MD in pregnancy?

Only under medical supervision. It may be prescribed in severe nausea (hyperemesis gravidarum) if benefits outweigh risks.

3. Can I take it while traveling?

Yes, it is ideal for motion sickness and does not require water for intake, making it travel-friendly.

4. Can it be used for anxiety?

It has mild antipsychotic/anxiolytic properties and may be used off-label for short-term anxiety in some cases.

5. What if I miss a dose?

Take the next dose as scheduled. Do not double up.

Conclusion

PROCHLOROMETIL MD is a fast-acting, effective, and easy-to-use mouth-dissolving tablet formulation of Prochlorperazine Maleate 5 mg, ideal for treating nausea, vomiting, and vertigo. Manufactured by Steris Healthcare Pvt. Ltd., it ensures quality, convenience, and therapeutic efficacy for patients needing rapid symptom relief.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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