NASAL FLUTICATONE & Fluticasone Furoate Nasal Spray: Uses, Dosage, Side Effects,Composition , ETC......

May 07, 2024

Introduction

NASAL FLUTICATONE is a highly effective fluticasone furoate nasal spray designed for the prevention and treatment of seasonal and perennial allergic rhinitis. Developed by Steris Healthcare Pvt. Ltd., this product offers powerful anti-inflammatory action directly at the nasal mucosa, reducing symptoms such as sneezing, nasal congestion, runny nose, and itching.Its once-daily dosing and advanced delivery system provide consistent relief with minimal systemic absorption.

What is Fluticasone Furoate?

Fluticasone Furoate is a synthetic corticosteroid specifically formulated for intranasal use. It exerts a strong local anti-inflammatory effect by inhibiting multiple types of cells and mediators involved in the allergic response.

As a second-generation corticosteroid, it has a favorable safety profile with low systemic bioavailability, making it suitable for long-term use in both adults and children (age criteria per physician guidance).

Mechanism of Action

The fluticasone furoate nasal spray works by:

  • Binding to glucocorticoid receptors in the nasal lining

  • Suppressing the release of pro-inflammatory cytokines

  • Reducing eosinophil activity and histamine release

  • Controlling vascular permeability in the nasal mucosa

This targeted anti-inflammatory response leads to quick and sustained relief from allergy symptoms.

Indications

NASAL FLUTICATONE is indicated for:

  • Seasonal Allergic Rhinitis (hay fever)

  • Perennial Allergic Rhinitis

  • Nasal Polyps (off-label use in some cases, per physician advice)

Dosage & Administration

Age Group Recommended Dose
Adults & Adolescents (≥12 yrs) 2 sprays in each nostril once daily (110 mcg)
Children (6–11 yrs)* 1 spray in each nostril once daily (55 mcg)
  • Shake well before use
  • Use at the same time every day

  • Maximum effect is usually seen after 3–4 days of regular use

*Use in children should be under medical supervision.

Clinical Benefits of Fluticasone FT Nasal Spray

  • Rapid symptom relief within 24 hours
  • Long-lasting effect – full-day control
  • Non-sedating, safe for daily use
  • Low systemic absorption – minimal side effects
  • Easy-to-use nasal applicator

Fluticasone FT Nasal Spray vs. Other Steroids

Compared to first-generation steroids like beclomethasone or budesonide, fluticasone furoate nasal spray offers:

  • Better receptor binding affinity

  • Higher potency at lower doses

  • Once-daily convenience

  • Fewer nasal side effects like crusting or dryness

Side Effects of Fluticasone Furoate Nasal Spray

Most users tolerate the spray well. However, potential side effects may include:

Common:

Rare but Serious:

  • Epistaxis (nosebleeds)

  • Nasal septum perforation (very rare)

  • Slowed growth in children (with prolonged use)

  • Hypersensitivity reactions

Discontinue use and consult a physician if severe or persistent symptoms occur.

Contraindications & Precautions

Avoid use in:

  • Patients with hypersensitivity to fluticasone or any component

  • Untreated nasal infections or tuberculosis

  • Recent nasal surgery or trauma

Precautions:

  • Monitor growth in children on long-term therapy

  • Use with caution in patients with glaucoma or cataracts

  • Regular cleaning of the nozzle is essential to prevent blockage

Drug Interactions

Minimal drug interactions, but caution should be taken if used with:

  • Ritonavir or strong CYP3A4 inhibitors – May increase systemic corticosteroid levels

  • Other corticosteroids – Risk of cumulative effects

Storage Instructions

  • Store below 30°C

  • Keep the cap tightly closed when not in use

  • Do not freeze

  • Keep out of reach of children

Product Summary

Attribute Details
Brand Name NASAL FLUTICATONE
Active Ingredient Fluticasone Furoate
Form Nasal Spray
Dosage Strength 27.5 mcg per spray
Pack Size 120 metered sprays
Usage Frequency Once daily (morning preferred)
Therapeutic Class Intranasal Corticosteroid
Manufacturer Steris Healthcare Pvt. Ltd.

FAQs – Fluticasone Furoate Nasal Spray

1. How long can I use NASAL FLUTICATONE?

It is safe for long-term use under medical supervision, especially in allergic rhinitis.

2. How quickly does it work?

Some relief may occur within 12–24 hours, but full benefit is seen after 3–4 days of daily use.

3. Can I use it with antihistamines?

Yes, it can be safely combined with oral antihistamines for more severe allergy symptoms.

4. Is it habit-forming?

No. Fluticasone furoate is not addictive and does not cause rebound congestion like decongestant sprays.

Conclusion

NASAL FLUTICATONE, containing fluticasone furoate nasal spray, offers powerful and sustained allergy relief for both seasonal and perennial rhinitis. Its superior potency, once-daily dosage, and low systemic exposure make it a preferred option among intranasal corticosteroids. Manufactured under stringent quality controls by Steris Healthcare Pvt. Ltd., this fluticasone ft nasal spray ensures safe, effective, and convenient treatment for allergy sufferers.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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