Manage Diabetes with GLISAXAPIN M 2.5/500 (Saxagliptin, Metformin)

May 22, 2024

GLISAXAPIN M 2.5/500 

Saxagliptin and Metformin, available under the brand name GLISAXAPIN M 2.5/500 by Steris Healthcare, is a prescription combination medicine used to manage type 2 diabetes mellitus effectively. Patients prescribed saxagliptin and metformin benefit from its dual-action mechanism, which helps maintain stable blood sugar levels, reduce post-meal spikes, and improve overall metabolic health.

Doctors often recommend GLISAXAPIN M 2.5/500 for patients who need combination therapy to control fasting and postprandial blood glucose levels. The sustained-release formulation of metformin ensures consistent blood sugar control throughout the day, making it easier for patients to manage their condition.

What Are Saxagliptin and Metformin?

Saxagliptin and Metformin combines two antidiabetic agents:

  • Saxagliptin 2.5 mg – A DPP-4 inhibitor that increases insulin secretion and decreases glucagon levels in response to meals.

  • Metformin ER 500 mg – A biguanide that reduces glucose production in the liver and improves insulin sensitivity in the body.

Together, these medicines provide complementary effects to control blood sugar, reduce HbA1c levels, and improve overall glycemic control in type 2 diabetes patients.

Uses of Saxagliptin and Metformin

GLISAXAPIN M 2.5/500 is prescribed for:

  • Managing type 2 diabetes mellitus in adults

  • Controlling fasting and post-meal blood sugar levels

  • Reducing the risk of diabetes-related complications such as neuropathy, kidney issues, and cardiovascular disease

  • Supporting weight management in patients with type 2 diabetes

The combination of saxagliptin and metformin allows patients to achieve better glucose control than monotherapy, often with fewer side effects.

How Saxagliptin and Metformin Work

Saxagliptin and metformin works through a dual mechanism:

  • Saxagliptin 2.5 mg increases insulin release from the pancreas and reduces glucagon secretion after meals, lowering blood sugar levels.

  • Metformin ER 500 mg decreases hepatic glucose production and enhances insulin sensitivity in body tissues.

  • This combination ensures steady blood sugar control throughout the day, reducing spikes and dips.

Dosage of Saxagliptin and Metformin

  • Typically, 1 tablet daily with meals, preferably with breakfast, or as prescribed by your doctor.

  • Swallow the tablet whole with water; do not crush or chew.

  • Dosage may be adjusted based on blood sugar monitoring and patient response.

  • Take at the same time every day to maintain consistent glucose control.

Side Effects of Saxagliptin and Metformin

Saxagliptin and Metformin Hydrochloride is generally well tolerated, but some patients may experience:

  • Nausea, vomiting, or mild stomach upset

  • Diarrhea or bloating

  • Headache or dizziness

  • Rarely, hypoglycemia (low blood sugar), especially if meals are skipped

  • Allergic reactions in sensitive individuals

Contact your doctor immediately if severe side effects occur or symptoms persist.

Precautions While Using Saxagliptin and Metformin

  • Monitor blood sugar levels regularly while on this medication.

  • Inform your doctor if you have kidney, liver, or heart conditions.

  • Avoid excessive alcohol as it may increase the risk of lactic acidosis with metformin.

  • Maintain a healthy diet and regular exercise to support blood sugar control.

  • Do not stop taking the medication abruptly; consult your doctor for guidance.

Why Choose Steris Healthcare for GLISAXAPIN M 2.5/500?

Steris Healthcare is committed to delivering high-quality, safe, and effective medications.GLISAXAPIN M 2.5/500 is manufactured in WHO-GMP-certified facilities, ensuring purity, efficacy, and patient safety.

Benefits of choosing Steris Healthcare include:

  • Reliable combination tablets for effective blood sugar control

  • Patient-friendly and doctor-recommended formulations

  • Affordable and widely available across India

  • Ethical manufacturing and strict quality assurance

Frequently Asked Questions

Q1: When should I take saxagliptin and metformin?
Take GLISAXAPIN M 2.5/500 with breakfast or as directed by your doctor to maintain consistent blood sugar levels.

Q2: Can this combination cause low blood sugar?
Yes, hypoglycemia can occur, especially if meals are skipped. Regular monitoring is advised.

Q3: Can I take this medication long-term?
Yes, under medical supervision, this combination is suitable for long-term management of type 2 diabetes.

Q4: Are there any dietary restrictions?
Follow a balanced diet and avoid excessive alcohol. Consult your doctor for a personalized diet plan.

Q5: Does saxagliptin and metformin help with weight management?
Metformin may support weight control, and lifestyle changes can enhance overall benefits.

Conclusion

Saxagliptin and Metformin offers effective, sustained blood sugar control for type 2 diabetes patients. Its dual-action mechanism, once-daily dosing, and doctor-recommended formulation help patients manage diabetes confidently while reducing complications.

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