GLISAXAPIN M 5/500 : Benefits, Uses, FAQs and Other Information.

Apr 24, 2024

GLISAXAPIN M 5/500 

Managing blood sugar levels is crucial for patients with type 2 diabetes. Saxagliptin and Metformin, marketed as GLISAXAPIN M 5/500 by Steris Healthcare, is a combination therapy designed to help patients achieve better glycemic control, improve insulin sensitivity, and maintain overall metabolic health.

This saxagliptin and metformin 5mg/500mg tablet combines saxagliptin 5mg, a DPP-4 inhibitor, with metformin HCl ER 500mg, a long-established antidiabetic agent. Together, they regulate blood glucose levels efficiently, making it a reliable choice for patients struggling with inadequate control from monotherapy

What is Saxagliptin and Metformin?

Saxagliptin and Metformin is a prescription medicine used for type 2 diabetes management. Saxagliptin helps increase insulin release and reduce glucagon levels, while Metformin ER decreases hepatic glucose production and improves insulin sensitivity.

This combination is particularly suitable for patients who do not achieve adequate blood sugar control with Metformin alone or require enhanced postprandial glucose management.

Uses of Saxagliptin and Metformin

The main indications for saxagliptin and metformin tablets include:

  • Management of type 2 diabetes mellitus

  • Control of fasting and post-meal blood glucose levels

  • Support for patients not adequately controlled on Metformin alone

  • Reducing the risk of diabetes-related complications through sustained glucose control

Saxagliptin and Metformin side effects are generally mild when used as prescribed, making it a safe option for long-term diabetes care.

How Saxagliptin and Metformin Work

Saxagliptin and Metformin acts through dual mechanisms:

  1. Saxagliptin 5mg (DPP-4 inhibitor) – Boosts incretin hormones, increasing insulin and lowering glucagon.

  2. Metformin HCl ER 500mg (Extended Release) – Reduces glucose production in the liver and improves peripheral insulin sensitivity.

This saxagliptin metformin combination ensures stable blood sugar levels with minimal risk of hypoglycemia when used properly.

Benefits for Patients

  • Effective blood sugar control

  • Reduces risk of diabetes-related complications

  • Convenient once-daily dosing

  • Minimizes postprandial glucose spikes

  • Safe for long-term type 2 diabetes management

Saxagliptin and metformin reviews show positive outcomes in patients achieving improved glucose control with minimal side effects.

Possible Side Effects

Common side effects of saxagliptin and metformin tablets include:

  • Mild nausea, vomiting, or stomach upset

  • Diarrhea or bloating (usually with Metformin)

  • Headache or dizziness

  • Rare: lactic acidosis (extremely uncommon, requires medical attention)

Patients should report severe or persistent symptoms to their healthcare provider immediately.

Precautions Before Using GLISAXAPIN M 5/500

  • Avoid if allergic to saxagliptin, metformin, or other ingredients

  • Not recommended in type 1 diabetes, diabetic ketoacidosis, or severe kidney/liver impairment

  • Regular blood sugar monitoring is advised

  • Take with meals to reduce gastrointestinal side effects

  • Inform your doctor about other medications, especially diuretics or heart medications

Why Choose Steris Healthcare?

 Choosing GLISAXAPIN M 5/500 from Steris Healthcare means:

  • WHO-GMP certified manufacturing ensures product safety and reliability

  • Affordable and widely available across India

  • Formulations designed for maximum patient efficacy

  • Patient-centric approach for safe and effective diabetes management

Frequently Asked Questions

Q1: What is Saxagliptin and Metformin used for?
It is used for managing type 2 diabetes, controlling both fasting and post-meal blood glucose levels.

Q2: Can Saxagliptin and Metformin cause hypoglycemia?
When used alone as prescribed, risk of hypoglycemia is low, but it may increase if combined with other antidiabetic medications.

Q3: How should GLISAXAPIN M 5/500 be taken?
Take once daily with meals to minimize gastrointestinal discomfort and ensure optimal absorption.

Q4: Are there side effects?
Mild nausea, stomach upset, diarrhea, or headache may occur. Rare serious effects like lactic acidosis need immediate medical attention.

Q5: Can Saxagliptin and Metformin be taken long-term?
Yes, under doctor supervision, it is safe and effective for long-term diabetes management.

Conclusion 

Saxagliptin and Metformin is a patient-friendly, effective, and convenient solution for type 2 diabetes management. It ensures better blood sugar control, improved insulin sensitivity, and reduced risk of diabetes complications.

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