Glimepiride & Metformin Hydrochloride Prolonged Release n

Glimepiride & Metformin Hydrochloride Prolonged Release

GLIMITERIS M1 

1. • Glimepiride:

     • Glimepiride belongs to a class of medications called sulfonylureas.
     • Mechanism of Action: It works by stimulating the release of insulin from the pancreas, which helps lower blood sugar levels.
     • Indications: Glimepiride is used to improve glycemic control in adults with type 2 diabetes mellitus, either as monotherapy or in combination with other antidiabetic medications.
     • Dosage: The typical starting dose of glimepiride is 1 to 2 mg once daily, taken orally. The dosage may be adjusted based on individual response and blood sugar levels, up to a maximum dose of 8 mg once daily.
     • Side Effects: Common side effects of glimepiride may include hypoglycemia (low blood sugar), weight gain, gastrointestinal symptoms (such as nausea or diarrhea), and allergic reactions.
     • Precautions: Glimepiride should be used with caution in patients with impaired liver or kidney function, as well as in elderly patients or those at risk of hypoglycemia.

   • Metformin Hydrochloride Prolonged Release:

     • Metformin belongs to a class of medications called biguanides.
     • Mechanism of Action: It works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, such as muscle and fat.
     • Indications: Metformin is used to improve glycemic control in adults with type 2 diabetes mellitus, either as monotherapy or in combination with other antidiabetic medications.
     • Dosage: Metformin hydrochloride prolonged release formulations are designed to provide extended-release of the medication, allowing for once-daily dosing. The typical starting dose is 500 mg once daily, with gradual dose titration as needed, up to a maximum dose of 2000 mg once daily.