Comprehensive Guide to Magral 40: Megestrol Acetate 40 mg

Introduction

MAGRAL 40 is a powerful oral formulation containing Megestrol Acetate 40 mg, a synthetic derivative of the hormone progesterone, widely used for managing anorexia, cachexia (weight loss), and hormone-responsive cancers like breast and endometrial carcinoma. It works as a progestin and appetite enhancer, especially helpful in patients suffering from unintentional weight loss due to chronic illness or cancer.

Composition Details

• Active Ingredient: Megestrol Acetate

• Strength: 40 mg

• Form: Oral tablet

• Packaging: Blister or strip (as per standard pack)

Mechanism of Action

Megestrol Acetate exerts its effects through multiple pathways:

1. Appetite Stimulation: It enhances appetite by acting on the hypothalamus and altering metabolism, which leads to increased calorie intake and weight gain.

2. Antineoplastic Activity: In hormone-responsive cancers, it acts as a progestational agent, inhibiting the growth of estrogen- and progesterone-sensitive tumor cells.

3. Anti-inflammatory and Anabolic Effects: It reduces protein catabolism and inflammation associated with chronic illness.

Uses of Megestrol Acetate 40 mg (MAGRAL 40)

Cancer Therapy:

• Palliative treatment of advanced or recurrent breast cancer

• Endometrial carcinoma

Appetite & Weight Loss Management:

• Anorexia

• Cachexia associated with AIDS, cancer, or other chronic conditions

• Significant unintentional weight loss

Note: MAGRAL 40 is not recommended for use in pregnant women or for birth control.

Megestrol Acetate Dosage (General Guidelines)

• Route: Oral

• Duration: As directed by a physician based on clinical condition and therapeutic response.

• Frequency: Once or twice daily

Always follow your doctor's prescription. The dosage may vary depending on individual medical needs.

Key Benefits of MAGRAL 40

• Effective in managing cancer-related weight loss
• Improves appetite and caloric intake
• Offers hormonal control in estrogen-sensitive cancers
• Convenient oral tablet formulation
• Cost-effective treatment option

Possible Side Effects of Megestrol Acetate 40 mg Tablets

While MAGRAL 40 is generally well-tolerated, possible side effects include:

Common:

• Weight gain

• Increased appetite

• Mild edema (fluid retention)

• Nausea

Less Common/Serious:

• Thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism)

• Hyperglycemia in diabetic patients

• Menstrual irregularities

• Adrenal suppression (rare with long-term use)

Important: Inform your doctor immediately if you notice swelling, chest pain, or difficulty breathing.

Precautions and Warnings

• Pregnancy Category X: Not to be used during pregnancy.

• Thromboembolic Risk: Caution in patients with a history of DVT or stroke.

• Diabetic Patients: Monitor blood glucose levels as MAGRAL 40 can increase insulin resistance.

• Adrenal Function: Long-term use may suppress adrenal glands; dose tapering may be necessary.

Drug Interactions

Megestrol Acetate may interact with:

• Anticoagulants (e.g., warfarin)

• Insulin or oral antidiabetic agents

• CYP3A4 substrates (consult your physician)

Always inform your doctor of all ongoing medications and supplements.

Storage Instructions

• Store at room temperature (below 30°C).

• Protect from moisture and light.

• Keep out of reach of children.

Why Choose MAGRAL 40 from Steris Healthcare?

•  Manufactured under WHO-GMP certified conditions
•  Clinically validated composition
•  Affordable and effective solution for serious clinical conditions
•  Backed by the trust of Steris Healthcare’s pharmaceutical excellence

Frequently Asked Questions (FAQs)

Q1. What is MAGRAL 40 used for?
A: MAGRAL 40 is used for appetite stimulation and weight gain in chronic illness and for treating hormone-responsive cancers such as breast and endometrial cancer.

Q2. How soon will MAGRAL 40 show results in appetite improvement?
A: Some patients may observe improvement within a few days, but full effects may take 1–2 weeks.

Q3. Can MAGRAL 40 cause blood clots?
A: Rarely, yes. Thromboembolic events are a known side effect and should be reported immediately if symptoms occur.

Q4. Is MAGRAL 40 a steroid?
A: No, it is a synthetic progestin, not a corticosteroid or anabolic steroid.

Q5. Can I take MAGRAL 40 during pregnancy?
A: No. It is contraindicated in pregnancy due to potential harm to the fetus.

Conclusion

MAGRAL 40 (Megestrol Acetate 40 mg Tablet) from Steris Healthcare Pvt. Ltd. provides a clinically effective, affordable, and patient-centric solution for managing weight loss in chronic illness and hormone-sensitive cancers. Whether used as an appetite stimulant or part of oncologic therapy, MAGRAL 40 delivers trusted therapeutic value and consistent outcomes.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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