Cefixime + Ofloxacin .. . .. . .

Introduction to CEFEXOTIME 0

CEFEXOTIME 0 is a powerful antibiotic combination that contains Cefixime (200mg) + Ofloxacin (200mg). This formulation is widely prescribed to treat a variety of bacterial infections, particularly those affecting the respiratory tract, urinary tract, gastrointestinal system, and soft tissues. By combining a cephalosporin antibiotic (Cefixime) with a fluoroquinolone antibiotic (Ofloxacin), CEFEXOTIME 0 provides broad-spectrum antibacterial coverage, ensuring effective treatment against both Gram-positive and Gram-negative bacteria.

Key Ingredients of CEFEXOTIME 0

1. Cefixime (200mg) – A third-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.

2. Ofloxacin (200mg) – A fluoroquinolone antibiotic that interferes with bacterial DNA replication, preventing bacterial multiplication and spread.

Uses of CEFEXOTIME 0

This combination antibiotic is used for treating a variety of bacterial infections, including:

• Respiratory Tract Infections: Bronchitis, pneumonia, sinusitis, and pharyngitis caused by susceptible bacterial strains.

• Urinary Tract Infections (UTIs): Including cystitis and pyelonephritis.

• Gastrointestinal Infections: Typhoid fever, traveler’s diarrhea, and bacterial dysentery.

• Sexually Transmitted Infections (STIs): Such as gonorrhea.

• Skin and Soft Tissue Infections: Cellulitis, abscesses, and wound infections.

• Ear and Throat Infections: Such as otitis media and tonsillitis.

How Does CEFEXOTIME 0 Work?

• Cefixime (200mg) inhibits peptidoglycan synthesis, a critical component of bacterial cell walls, making the bacteria structurally weak and leading to its destruction.

• Ofloxacin (200mg) inhibits bacterial DNA gyrase and topoisomerase IV, preventing the bacteria from replicating, thereby controlling the infection.

This dual-action mechanism ensures enhanced effectiveness, reducing bacterial resistance while promoting rapid recovery.

Dosage & Administration

• The usual dosage for CEFEXOTIME 0 in adults is one tablet (200mg Cefixime + 200mg Ofloxacin) twice daily.

• It should be taken with or without food, preferably with a full glass of water.

• The course should be completed as prescribed by a healthcare professional, even if symptoms improve early.

• Missed Dose: If a dose is missed, take it as soon as possible. However, if it’s close to the next scheduled dose, skip the missed one.

• Overdose: In case of an overdose, seek immediate medical attention.

Side Effects of CEFEXOTIME 0

Like any medication, CEFEXOTIME 0 may cause some side effects. Common side effects include:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, abdominal pain.

• Headache & Dizziness: Mild to moderate.

• Allergic Reactions: Rash, itching, swelling of the face/lips/tongue (seek immediate medical help if severe).

• Liver Enzyme Elevations: Monitor liver function if used for prolonged periods.

• Yeast Infections: Due to an imbalance in natural bacterial flora.

Precautions & Warnings

• Allergy Alert: Avoid if allergic to cephalosporins, penicillins, or fluoroquinolones.

• Kidney or Liver Issues: Should be used with caution in patients with renal or hepatic impairments.

• Pregnancy & Breastfeeding: Consult a doctor before use.

• Tendon Rupture Risk: Fluoroquinolones (like Ofloxacin) may increase the risk of tendonitis or tendon rupture, particularly in elderly patients.

• Drug Interactions:

  • Avoid combining with antacids, multivitamins, or dairy products, as they may reduce Ofloxacin absorption.

  • Warfarin & Blood Thinners: Increased risk of bleeding.

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): May increase the risk of seizures.

Advantages of CEFEXOTIME 0 Over Other Antibiotics

1. Dual Mechanism: Targets both cell wall synthesis & bacterial DNA replication, enhancing effectiveness.

2. Broad-Spectrum Action: Effective against multiple bacterial strains.

3. Faster Recovery: Works rapidly to relieve infection-related symptoms.

4. Lower Resistance Development: The combination reduces bacterial resistance compared to single-drug therapy.

5. Convenient Dosage: Twice-daily dosing ensures patient compliance.

Price & Availability in India

The approximate price of CEFEXOTIME 0 varies depending on the brand and pharmacy. Generally, a strip of 10 tablets is available within the range of ₹200 - ₹500. It is available at local pharmacies and online drugstores.

Conclusion

CEFEXOTIME 0 (Cefixime 200mg + Ofloxacin 200mg) is a powerful antibiotic combination designed to combat a wide range of bacterial infections. With its broad-spectrum activity, rapid relief, and dual-action mechanism, it remains a go-to choice for treating various respiratory, urinary, and gastrointestinal infections. However, it is crucial to follow the prescribed dosage, complete the full course, and be aware of potential side effects. Always consult a healthcare provider before using this medication to ensure its suitability for your condition.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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