Benidipine (4mg), Metoprolol Succinate (50mg) ""

Aug 14, 2023

Introduction

BENIPRIME M 50 is a highly effective oral medication formulated to treat high blood pressure (hypertension) and associated cardiovascular conditions. This powerful combination features two clinically proven antihypertensive agents: Benidipine (4mg) and Metoprolol Succinate (50mg). These ingredients work in synergy to provide comprehensive control over blood pressure and heart function, reducing the risk of heart attacks, strokes, and other heart-related complications.

With the prevalence of hypertension growing rapidly across age groups, especially in urban lifestyles, BENIPRIME M 50 emerges as a trusted therapeutic solution to keep blood pressure levels in check. Whether you’re dealing with borderline hypertension or chronic cardiovascular disease, this medication offers multi-targeted benefits.

About This Medication

BENIPRIME M 50 belongs to a class of medications known as antihypertensives. It is a fixed-dose combination tablet that contains two potent drugs:

  • Benidipine (4mg) – a calcium channel blocker

  • Metoprolol Succinate (50mg) – a beta-blocker

Let’s dive deeper into each component:

Benidipine (4mg)

Also referred to in some medical references as tab benidipine or benidipine 4 mg, Benidipine is a third-generation dihydropyridine calcium channel blocker. It helps relax blood vessels, making it easier for the heart to pump blood efficiently, thereby reducing blood pressure. It also has renal-protective and anti-anginal properties.

This compound is known for its long-acting effect and high vascular selectivity, making it a preferred option in managing both hypertension and angina.

Metoprolol Succinate (50mg)

Metoprolol Succinate is a selective beta-1 receptor blocker that slows down the heart rate, reduces cardiac output, and lowers blood pressure. It is often used for managing hypertension, angina, and heart failure. The sustained-release formulation ensures consistent blood levels over 24 hours.

Together, these agents provide dual-action blood pressure control and cardiovascular protection.

Uses

BENIPRIME M 50 is primarily used for the management and treatment of:

1. Hypertension (High Blood Pressure)

The combination of Benidipine (4mg), Metoprolol Succinate (50mg) significantly reduces elevated blood pressure by relaxing blood vessels and reducing the heart rate. It is suitable for patients with mild, moderate, or severe hypertension.

2. Chronic Stable Angina

This medication improves blood flow to the heart, relieving chest pain and preventing episodes of angina, especially during physical exertion or stress.

3. Cardiovascular Risk Reduction

By lowering blood pressure and heart rate, BENIPRIME M 50 minimizes the risk of heart attacks, strokes, and heart failure.

4. Left Ventricular Hypertrophy (LVH)

The calcium channel blocking effect of benidipine hydrochloride helps reduce ventricular thickening associated with long-term hypertension.

5. Renal Protection in Hypertensive Diabetics

Benidipine 4 mg has shown renal-protective properties, making it useful in patients with hypertension and early signs of kidney dysfunction.

Dosage

The usual dosage of BENIPRIME M 50 is one tablet daily, preferably taken at the same time each day. It should be consumed with or without food, as advised by your physician.

Important Dosage Guidelines:

  • Do not crush or chew the tablet. Swallow it whole with water.

  • Take it at the same time each day to maintain even drug levels.

  • Do not stop abruptly, especially Metoprolol Succinate (50mg), as sudden withdrawal may lead to adverse cardiac events.

  • Adjustments may be necessary for individuals with liver or kidney issues.

  • Monitor blood pressure and heart rate regularly during therapy.

Always follow your healthcare provider's instructions to ensure safe and effective use.

What Are the Possible Side Effects of This Medicine?

While BENIPRIME M 50 is well tolerated by most patients, some individuals may experience mild to moderate side effects. These effects are generally temporary and subside as your body adjusts to the medicine.

Common Side Effects:

  • Dizziness or lightheadedness – especially when rising suddenly

  • Fatigue or tiredness – common with beta-blockers

  • Slow heart rate (bradycardia)

  • Swelling in the ankles or feet – due to vasodilation

  • Headache – particularly during initial treatment days

  • Flushing or warmth – due to benidipine hydrochloride

Less Common Side Effects:

  • Palpitations or irregular heartbeat

  • Shortness of breath

  • Cold extremities

  • Low blood pressure (hypotension)

  • Sleep disturbances or vivid dreams

  • Nausea, constipation, or abdominal discomfort

If any side effect worsens or persists, it is essential to seek immediate medical advice.

Frequently Asked Questions (FAQs)

What is BENIPRIME M 50 used for?

BENIPRIME M 50 is prescribed to manage high blood pressure and prevent complications such as strokes, heart attacks, and kidney problems. It is also effective in treating chronic stable angina and other cardiovascular conditions.

What are the active ingredients in BENIPRIME M 50?

This medication contains Benidipine (4mg) and Metoprolol Succinate (50mg) as its active ingredients.

How does Benidipine 4 mg work?

Benidipine 4 mg works by blocking calcium channels in the vascular smooth muscles, causing them to relax. This leads to a decrease in peripheral resistance and blood pressure.

Can I stop taking BENIPRIME M 50 if my blood pressure is normal?

No, do not stop taking the medicine without consulting your doctor. Stopping suddenly can cause blood pressure to rise again or lead to cardiac complications.

Are there any dietary restrictions while on this medication?

Limit your salt intake, avoid alcohol, and follow a heart-healthy diet. Incorporate regular exercise and maintain a healthy weight.

Can I take BENIPRIME M 50 with other medications?

Inform your doctor of all other medicines you are taking, especially for diabetes, depression, asthma, or heart conditions, to avoid drug interactions.

Is this medicine suitable for elderly patients?

Yes, but dosage and kidney/liver function monitoring are essential, as elderly patients are more sensitive to antihypertensive effects.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. However, if it's almost time for the next dose, skip the missed one. Do not double the dose to make up for it.

Final Thoughts

BENIPRIME M 50 is a scientifically backed combination therapy that provides comprehensive management of hypertension and cardiovascular conditions. With Benidipine (4mg) providing potent vascular relaxation and Metoprolol Succinate (50mg) offering excellent heart rate control, the tablet ensures holistic cardiovascular protection.

The formulation is ideal for patients requiring a dual-action approach to high blood pressure, especially those who haven't responded well to monotherapy. It is a valuable addition to the hypertension treatment spectrum, reducing the risk of serious complications while promoting long-term wellness.

Patients using BENIPRIME M 50 should remain compliant with the prescribed regimen, maintain regular follow-ups, and adopt a healthy lifestyle to optimize therapeutic benefits.

In conclusion, whether you're seeking better control over your blood pressure, reducing angina episodes, or improving heart health, BENIPRIME M 50 powered by benidipine hydrochloride and metoprolol succinate offers reliable, clinically effective support.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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